Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Cosmetic Ingredients Functions
- CAS No.
- 5306-85-4
- Technologies
- Product Families
- Chemical Structure
Features & Benefits
- Benefit Claims
- Characteristics
- Vehicle for cosmetics and pharmaceutical actives;
- Wide range of applications;
- Improved delivery of active ingredients in topical applications, including:
- Dihydroxy Acetone (DHA) for self-tanning products
- Benzoyl peroxide in anti-acne formulations
- Various other actives, whether soluble in water or with little solubility, e.g. hydrocortisone, salicylic acid, lactic acid, acetylsalicylic acid
- Vitamins C, E & K, hyaluronic acid (lips), bioflavonoids, kojic acid, hydroquinone, estrogen etc.
- Help in asset stability
- Stable to hydrolysis
- Miscible with a wide range of ingredients, including most organic solvents and
- Non-ionic surfactants
- Excellent security profile, long history of safe use.
- High boiling point, low volatility, low viscosity.
- Benefits
- Allows efficient delivery and improves penetration of hydrophilic actives into the skin.
- For cosmetic and pharmaceutical use, it allows the material to be used in a wide range of products.
- Allows for cost savings due to a reduction in the amount of assets, less irritation caused by aggressive assets, providing the same effectiveness with fewer assets that will give the same effect and will be more effective.
- In the case of use for self-tanning products, there is a rapid development of colors with greater longevity in tanning. The tan develops more evenly with fewer streaks or stains.
- Increased penetration of assets through the epidermis allowing for effective and improved asset delivery.
- Can be used in a wide range of applications to reduce the cost of formulations or improve formulations. effects.
- Provides better product storage stability for formulations containing unstable actives, particularly those susceptible to hydrolysis or transesterification.
- Miscible with all proportions of water without concerns about hydrolysis occurring.
- Wide formulation spectrum with excellent shelf stability allowing incorporation into a wide range of products: - E.g. clear gels, foam creams, lotions, sprays and ointments.
- Produces light formulations with reduced irritation potential.
- Allows the transport of water-soluble assets to the skin, without recrystallization of the asset.
- Allows the production of formulations in conventional equipment without the need to handle flammable materials.
- Improvement In Asset Delivery With Pureskin DM®
PureSkin DM® (INCI: Dimethyl Isosorbide) can be used to help permeate actives in the epidermis where they will act most effectively. While providing excellent targeted delivery of the asset to the epidermis, PureSkin DM does not promote penetration of the asset into the blood flow. Examples of Assets found with PureSkin DM®:
- Dihydroxyacetone
- Benzoyl peroxide
- Hydrocortisone
- Salicylic acid
- Lactic acid
- Acetylsalicylic acid
- Vitamins C, E, K
- Hyaluronic acid
- Kojic acid
- Estrogen
- Testosterone and more.
Applications & Uses
- Markets
- Application Format
- Hair Care Applications
- Nail Care Applications
- Skin Care Applications
- Sun Care Applications
- Treatment Product Applications
- Commercial Applications
- Anti-dandruff products
- Oral care
- Serum for hair loss treatment
- Skin whitening products
- Self tanning products
- Anti-Acne Products
- AHA/BHA Products
- Nail polish remover
- Make-up remover makeup remover
- Pharmaceutical formulations
- Potential Use
- Activation of assets
- Topical application improver of:
- AHA, BHA
- Organic sunscreens
- Skin lightening agents
- Anti-acne actives (Benzoyl Peroxide)
- Vitamins
- Self tanning agents
- Skin moisturizing agents (Hyaluronic Acid)
- Vegetable extracts
- Delivery of anti-inflammatory drugs.
- Current Use
Examples of appeals found in the literature of commercial products:
- Used to facilitate absorption into leather hair and follicle;
- Formulated with grade cutaneous penetration active pharmacist, promoting the permeation of the vitamin C on the skin;
- Promotes skin permeation;
- Proven capacity of dimethyl isosorbide from skin permeation.
Properties
- Physical Form
- Appearance
- Clear colorless liquid
- Soluble in
- Emollients, cottonseed oil, isopropanol, isopropyl myristate, propylene glycol, polysorbate 20 or polysorbate 80, surfactant and water
- Insoluble in
- Hydrogenated castor oil, lanolin and mineral oil
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Acidity | max. 1.5 | mgKOH | - |
| Dimethyl Isosorbide Content | min. 99 | % | - |
| Water Content | max. 1 | % | CLI - WATER |
| Freezing Point | max. -70 | °F | |
| Refractive Index (25°C) | approx. 14601 | - | - |
| Specific Gravity (25°C) | approx. 1.61 | - | - |
| Steam Pressure (25°C) | approx. 2 | mmHg | - |
| Viscocity (25°C) | approx. 6 | cst | - |