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LIPOCLARE

3% Kojic acid liposomes. Unlike traditional liposomes formulated with soy lecithin and manufactured with basic methods, In Dermal technology offers new generation vesicles, applying medical technology to dermo cosmetics.

INCI Name: Cholesterol, Kojic Acid, Mannitol, Phosphatidylcholine, Polysorbate 80, Sodium Chloride, Tocopheryl Acetate, Xanthan Gum

Functions: Anti-Pigmentation Agent

Ingredient Origin: Natural Origin

Labeling Claims: Clean at Sephora, Natural, Naturally Derived, Ulta Beauty's Conscious Beauty

Benefit Claims: Age & Dark Spot Reduction, Anti-Aging, Brightening, Dermal Metabolism Enhancement, Even Skin Tone, Excellent Stability, Melanin Reduction, Photo-Aging Protection, Pigmentation Reduction, Skin Barrier, Skin Protection, Skin Whitening, UV Protection

Technical Data Sheet
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Knowde Enhanced TDS

Identification & Functionality

Ingredient Origin
Cosmetic Ingredients Functions

Features & Benefits

Key Attributes
  • Very stable and resistant
  • Maximized effectiveness
  • Smart release system
  • Biomimetic composition
  • Increased potency while improving the active ingredient safety and stability: x8.16 compared to free Kojic acid.
Marketing Claims
  • Dermocosmetic technology
  • Anti-photoaging
  • Depigmenting
  • Skin brightener & tone corrector
  • UV protection
  • Prevents premature aging
  • Prevents age spots
  • Phospholipids from pharmaceutical grade
  • Biomimetic liposomes
  • Less active ingredient for same activity.
  • x8,16 more effective than free Kojic acid.

Applications & Uses

Application Format
Use Level
1% - 10%

Properties

Dispersible in
Water

Technical Details & Test Data

Depigmenting Activity - Melanin Quantification
  • Ex-vivo test in human skin.
  • Skin exposure to UV radiation at T=1, T=2, T=3 and T= 4 days.
  • Addition of the tested products (LIPOCLARE and free Kojic acid) at T=2, T=3 and T=4 days.
  • Quantification of melanin at T=5.

Results: Immediate Activity Melanin Reduction in just 5 days

 

Immediate Efficacy

2,22% LIPOCLARE proved to be much more effective than free Kojic acid, reducing the amount of melanin to levels close to the non-irradiated control in just 5 days.

Melanin synthesis (μg)

LIPOCLARE - Depigmenting Activity - Melanin Quantification

*2.22% LIPOCLARE is equivalent to 0.066% free kojic acid

The Concentration of Lipoclare

The Concentration of Lipoclare was X1.25 times higher in the Stratum Corneuma nd X8.16 times higher in the Basal Epidermis.

LIPOCLARE - The Concentration of Lipoclare