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Starpharma Holdings Limited (ASX:SPL, OTCQX:SPHRY) is a global biopharmaceutical company and a world leader in the development of new pharmaceutical and medical products based on proprietary polymers called dendrimers, with programs for COVID-19, DEP® drug delivery and VivaGel®. Starpharma has developed VIRALEZE™, an antiviral nasal spray for COVID-19, which is complementary to vaccines and other preventative measures such as distancing and PPE. VIRALEZE™ is registered for sale in the UK/Europe and available in the UK through LloydsPharmacy. SPL7013 is utilized in approved products - the VivaGel® condom and VivaGel® BV. VivaGel® BV has been licensed in >160 countries, is approved in >45 countries and available for sale in the UK, Europe, Japan, South East Asia, Australia and New Zealand.

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Benefits of DEP® is used to improving efficiency, reducing toxic side effects of drugs, extending the duration of activity of the drug in the body, targeting drugs to Organs, tissues or molecular receptors, increasing solubility.

DEP® cabazitaxel is Starpharma’s detergent-free version of cancer drug, Jevtana®, which is marketed by Sanofi Aventis to treat advanced prostate cancer, and is also under clinical development for a range of other cancer types, including testicular, ovarian, breast, bladder, and head and neck.


DEP® cabazitaxel

DEP® irinotecan is a novel, patented nanoparticle formulation of SN-38, the active metabolite of irinotecan, delivered using Starpharma’s proprietary DEP® technology. DEP® irinotecan has shown a number of benefits compared to the original form of irinotecan, including significant improvements in anti-cancer efficacy and improved survival in multiple human cancer models. DEP® irinotecan is the third DEP® product to enter the clinic from Starpharma’s internal portfolio.

DEP® irinotecan

DEP® docetaxel is water-soluble and does not require surfactant such as polysorbate 80 for dissolution. Drug substance is readily manufactured at scale using standard chemistry under cGMP.

DEP® docetaxel

DNT (Starpharma Group)

Starpharma Holdings Limited (ASX:SPL, OTCQX:SPHRY) is a global biopharmaceutical company and a world leader in the development of new pharmaceutical and medical products based on proprietary polymers 

DNT (Starpharma) - VIRALEZE - COVID-19 - DEP - VivaGel®

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Pharmaceuticals & Nutraceuticals - DNT (Starpharma Group) - Knowde

Starpharma AACR Poster 1716 DEP docetaxel DEP cabazitaxel

DEP® docetaxel Starpharma's dendrimers improve efficacy of docetaxel in animals 

DEP® docetaxel Starpharma's docetaxel demonstrates targeted tumour delivery

DNT (Starpharma Group)Drug Delivery Summary 

Starpharma AACR Poster 1715 DEP irinotecan

DEP® docetaxel Docetaxel eliminates neutropenia 

DEP® irinotecan DEP® irinotecan synergistic with Lynparza® in refractory human colon cancer model 

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