Aflocox® Plus

Identification & Functionality

Animal Feed & Nutrition Functions

Anticoccidial

Technologies

Animal Feed & Nutrition

Product Families

Animal Feed & Nutrition — Health & Well-Being

Antibiotics & Anti-Infective Agents

Components

Mixture of dried herbs, plant extracts, pigment, esterified fatty acids (butyric, lauric), sorbic acid, medium chain fatty acids (capric, caprylic), calcium propionate, essential oils and anticaking agents.

Features & Benefits

Animal Feed & Nutrition Features

Antioxidant Effect,

Improves Immunity,

Prevents Oxidative Stress,

Reduces Inflammation

Product Background

• A novel alternative approach to control coccidiosis which contains triterpenoid saponins that bind to the cholesterol of the protozoan cell membrane. Several bio-active immunomodulatory compounds reinforce the bird’s immunity during coccidiosis infection. The antioxidant bio-actives can alleviate the excess of the oxidative stress during infection. The plant bio-actives have been selected for their ability to reduce the acute inflammation encountered during coccidiosis.
• Complementary to this beneficial molecule, essential oils, plant extracts and specific fatty acids support the natural symbiosis between host and microflora under stressful conditions

Product Benefits

• Anti-parasitic effect - Aflocox^® interferes with the Eimeria cell wall synthesis Aflocox^® contains triterpenoid saponins that bind to the cholesterol of the protozoan cell membrane. This leads to incomplete oocyst wall synthesis and eventually to partial cell lysis and cell death.
• Enhancing immunity - Aflocox^® contains several bio-active immunomodulatory compounds (Saponins, Terpenoids) that reinforce the bird’s immunity during coccidial infection.
• Reducing oxidative stress - Phenolics, Flavonoids, Carotenoids. Reactive oxidative species are produced by the host’s cellular immune response during the invasion by Eimeria species. Although this plays a role in defending against parasitic infections, when concentrations exceed a certain level, they cause tissue damage and cytotoxicity. The antioxidant bio-actives within Aflocox^® can alleviate excessive oxidative stress.
• Ameliorating inflammatory challenge - Saponins, Alkaloids. Upon invasion of Eimeria, a strong inflammatory response is induced which results in the destruction of the intestinal villi, diarrhea, hemorrhage cases, and, death in severe cases. The plant bio-actives within Aflocox^® reduce the acute inflammatory response during coccidial infection.

Key Benefits

• Prevents anticoccidial resistance
• No withdrawal period
• Better economics
• Prevent feed cross contamination
• No resistance build-up
• Stable to pelleting

Applications & Uses

Markets

Agriculture & Feed

Applications

Agriculture & Feed — Animal Health & Nutrition

Birds & Poultry

Animal Species

Broilers,

Turkey

Use Level

0.5 - 1.5 kg/T (Poultry)

Product Applications

Helps to improve coccidiosis control, intestinal health and performance of broilers and turkeys reared:

• in an antibiotic-free environment
• in conventional systems facing growing resistance to existing inonophores or synthetic treatments
• fully compatible with coccidial vaccine programs

Properties

Physical Form

Powder,

Solid

Physical Properties

	Value	Units	Test Method / Conditions
pH (in 10% Solution)	4.1 - 5.1	—	—
Specific Gravity	0.49 - 0.69	kg/l	—
Moisture Content	max. 5	%	—

Technical Details & Test Data

Average NIR Spectrum

Aflocox® Plus vs Combined Formula of Ionophore + Chemical

D0 - D21
Control	Trial
Narasin + Nicarbazin	Aflocox® Plus (1 kg/T)

Aflocox® Plus vs combined formula of Ionophore + Chemical during starter & grower period

Aflocox® in Challenging Feed vs Non-challenging Feed

Aflocox® in challenging feed vs regular anticoccidial program in non-challenging feed

Feed	Group	Treatment
Mash wheat-rye based diet + 5% rye • No coccidiostat • No NSP enzymes • No antibiotics	Positive control	No treatment
	Aflacox®	Aflacox® 0.5 kg/T
	Aflacox® Plus	Aflacox® Plus 1 kg/T
Corn – Soy diet • No antibiotics	Negative control	D0 – D21: Monensin + Nicarbazin D22 – D35: Salinomycin

 

Coccidia lesion score: Eimeria acervulina, maxima, tenella

 

Packaging & Availability

Packaging Type

Bags

Packaging Information

• Standard 20 kg export worthy bags on wooden fumigated pallets.
• Other net weights (1 kg*, 5 kg*, 10 kg, 750-1000 kg, bulk) on demand.

*Marked unit packs are packed in an outer carton up to max. 25 kg.

Storage & Handling

Shelf Life

2 Years

Storage Conditions

24 months when stored in a cool and dry environment out of direct sunlight in unopened packing.