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Actifcol™ advanced botanical ingredient

1 of 1 products in this brand
Actifcol™ advanced botanical ingredient, that smooths, tightens, and firms skin while boosting collagen. Crafted from natural, plant-based, and organic ingredients, it meets ulta beauty's conscious beauty, and credo clean standard and is halal-certified. Benefit from its highly restructuring properties, skin-smoothing effects, and visible improvements in skin appearance, tightness, firmness, and collagen enhancement.

INCI Name: Lentinus Edodes Extract, Phytic Acid, Potassium Sorbate, Sodium Benzoate, Sodium Citrate

Ingredient Origin: Natural Origin, Non-Animal Origin, Plant Origin

Benefit Claims: Collagen Boosting, Firming, Highly Restructuring, Improves Skin Appearance, Skin Tightening, Smoothing

Labeling Claims: Clean at Sephora, Credo Clean Standard, Halal, Natural, Naturally Derived, Organic, Plant-Based, Ulta Beauty's Conscious Beauty

Certifications & Compliance: CFDA Compliant (China), COSMOS, ECOCERT, Halal, ISO 16128, Organic Certified

Synonyms: Inositol 1,2,3,4,5,6-hexakisphosphate, Inositol Hexakis(phosphate), Inositol Hexaphosphate, Inositol, Hexakis(dihydrogen Phosphate), Myo -, meso -Inositol Hexaphosphate, myo -Inositol Hexakis(phosphate), myo -Inositol Hexaphosphate, myo -Inositol, 1,2,3,4,5,6-hexakis(dihydrogen Phosphate), myo -Inositol, Hexakis(dihydrogen Phosphate)

Knowde Enhanced TDS

Identification & Functionality

Carrier

Aqua,

Glycerin,

Solvent-based

INCI Name

Lentinus Edodes Extract,

Phytic Acid,

Potassium Sorbate,

Sodium Benzoate,

Sodium Citrate

Ingredient Origin

Natural Origin,

Non-Animal Origin,

Plant Origin

Technologies

Cosmetic Ingredients

Product Families

Cosmetic Ingredients — Vitamins, Extracts & Oils

Botanical Ingredients & Extracts

Features & Benefits

Benefit Claims

Collagen Boosting,

Firming,

Highly Restructuring,

Improves Skin Appearance,

Skin Tightening,

Smoothing

Labeling Claims

Clean at Sephora,

Credo Clean Standard,

Halal,

Natural,

Naturally Derived,

Organic,

Plant-Based,

Ulta Beauty's Conscious Beauty

Product Highlights

Science

  • The loss in skin firmness mostly results from a decrease in the synthesis of collagen and an increase in its deterioration. Type I collagen is one of the most abundant proteins in the skin, providing tissue structure and strength. Its proper structural and biological functions are the outcome of a post-translational modification (PTM), a critical step during biosynthesis that involves the hydroxylation of lysine residues by an enzyme encoded by the PLOD gene.
  • Collagen can also experience the deterioration process of carbamylation, related to a destabilization of the triple helix and an accumulation of derived products associated with a loss of elasticity and sagginess.
  • ActifcolTM advanced botanical ingredient has a potential activity in increasing type I collagen and PLOD1 levels, as well as in reducing carbamylation of such protein. On mature skin, an improvement in firmess was measured and a decrease in flaccidity was observed in the face, neck and décolleté.
Product Benefits
  • Increased PLOD1 for an enhanced collagen quality
  • Reduced carbamylation, a protein deterioration process
  • Improved appearance at neck and decollete

Applications & Uses

Markets

Personal Care

Applications

Personal Care — Beauty & Care

Skin Care

Application Format

Creams

Skin Care Applications

Body Cream

Use Level
2.0 - 10.0%

Properties

Physical Form

Liquid

Appearance
Liquid containing 1% Lentinus Edodes Extract.
Soluble in
Water
Typical Properties
ValueUnitsTest Method / Conditions
Natural Origin97.96%ISO 16128

Regulatory & Compliance

Certifications & Compliance

CFDA Compliant (China),

COSMOS,

ECOCERT,

Halal,

ISO 16128,

Organic Certified

Technical Details & Test Data

In Vitro Efficacy

1. Type I Collagen Induction
Fibroblasts were treated with 1% actifcolTM advanced botanical ingredient and the amount of type I collagen was assessed by an ELISA.

Result : 36.6% increase in key dermal protein levels


2. Increase in Plod1
Fibroblasts were treated with 2% or 3% actifcolTM advanced botanical ingredient and an ELISA was used to measure the levels of PLOD1.

Result :PLOD1 boost, suggesting an improved collagen quality


3. Decrease in Carbamylation
Type I collagen was incubated with potassium cyanate, to simulate the carbamylation process, and with 2% actifcolTM advanced botanical ingredient. Carbamylation was evaluated with a protein carbamylation ELISA kit.

Result :1. Reduction in the collagen deterioration
             2. Carbamylation levels decreased by 75.9% versus control.

In Vivo Efficacy

Enhancemet in Firmness

19 women (41-55 years old) with skin flaccidity applied a cream with 2% actifcolTM advanced botanical ingredient on the neck, décolleté and half face and a placebo cream on the other half, twice a day for 56 days.

1. Maximal deformation

The parameter was evaluated with a cutometer, which allows the quantification of firmness, being a decrease in maximal deformation (R0) associated with a firmer skin.

 

- 1

 

Result : Statistically significant improvement in face, neck and décolleté firmness

 

2. Anisotropy

The linearity of the skin (anisotropy), which determines the displacement and returningprofile, was assessed by a device that combines a mechanical force and imaging. This provides a 3D view of the suction and return of the skin to the starting point.

 

- 2

 

Result : More isotropic skin with an even return to the starting point

 

3. Visible tightness

The efficacy against flaccidity was appraised through macro photographs of the volunteers.

 

- 3

 

Result : Demonstrated firmer and smoother complexion