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DISOLCEL® CCS (Croscarmellose Sodium)

1 of 2 products in this brand
Disolcel® CCS (Croscarmellose Sodium) is an internally cross-linked Carboxymethylcellulose Sodium, and it is essentially water-insoluble, yet rapidly swelling and absorbing many times its weight in water. As a result, it provides superior tablet disintegration and aids in dissolution of the active ingredient, thus ensuring the bioavailability of the drug/supplement. Disolcel® possesses consistent disintegrative functionality due to above mentioned properties, which contribute to the low use level for having the excellent disintegration and dissolution.

Chemical Name: Croscarmellose Sodium

CAS Number: 74811-65-7

Functions: Disintegrant

Labeling Claims: Non-GMO

Certifications & Compliance: British Pharmacopeia (BP), European Pharmacopeia (Ph. Eur.), Japan Pharmacopeia (JP), National Formulary (NF), United States Pharmacopeia (USP)

Synonyms: E468, Sodium Croscarmellose

    Knowde Enhanced TDS

    Identification & Functionality

    Pharma & Nutraceuticals Functions
    CAS No.
    74811-65-7
    EC No.
    629-739-2

    Features & Benefits

    Labeling Claims
    Benefits
    • Rapid disintegration
    • Aid in dissolution
    • Ensuring the bioavailability of active ingredient
    • No effect on the compressibility and flowability
    • Cost-effective at low use level
    Product Highlights

    Meets the Requirement for Pharmaceutical and Food applications
    Disolcel® complies with the monograph requirements of current edition of the pharmacopeias:USP/NF, EP, BP and JP.

    Applications & Uses

    Properties

    Typical Properties
    ValueUnitsTest Method / Conditions
    Loss on Dryingmax. 10.0%
    Settling Volume'10-30ml
    Degree of Substitution0.60 - 0.85

    Regulatory & Compliance

    Technical Details & Test Data

    Effect of Settling Volumes in Disolcel® on Drug Dissolution

    The data below shows that formulation containing Disolcel® with higher settling volume, has faster drug dissolution that means speed up the drug released rate. (i.e the shorter T60%)

    DISOLCEL® CCS (Croscarmellose Sodium) - Effect of Settling Volumes in Disolcel® On Drug Dissolution