Knowde Enhanced TDS
Identification & Functionality
- Carrier
- Chemical Family
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Information
Nano Nails is a natural cosmetic ingredient consisting of a blend of essential oils of lemongrass, melaleuca and clove, encapsulated in high permeation nanoparticles with proven clinical efficacy in the repair of damaged nails, with dull, whitish and brittle appearance, usually diagnosed as leukonychia.
Lemongrass Essential Oil
Lemongrass is a plant originally from Asia, mainly from India. From it is extracted an essential oil whose main component is Citral (Geraniol) largest responsible for the antifungal, anti-microbial, anti-inflammatory and analgesic properties of this oil.
Clove Essential Oil
Clove is a dried flower bud from a tree native to the Moluccas, Indonesia. The properties of its essential oil are attributed to its main constituent, eugenol, which has an important antibacterial and antifungal effect.
Melaleuca Essential Oil
The main component of Melaleuca essential oil is terpinen-4-ol, which, according to studies, is responsible for antimicrobial and antiseptic actions that occur through a leukocyte activation mechanism. Its antimicrobial action includes fungi, yeasts, gram-negative bacteria and the herpes simplex virus.
According to HAMMER, Melaleuca essential oil can cause allergic reactions in predisposed individuals. These reactions are caused not by the oil itself, but due to oxidation reaction byproducts that occur by exposure of components to light and oxygen. Encapsulation of the active ingredient promotes controlled release and protects the interaction with the other components of the formula and the environment, preventing oxidation and avoiding potential skin irritation. Encapsulation also promotes occlusion of the characteristic odor of Melaleuca essential oil, ensuring an improvement in the sensory experience of the final product.
- Product Features
Particle: Lipid
Release Trigger: Enzyme
- Marketing Appeals
- Strengthens nails;
- Moisturizes nails and cuticles;
- Repairs white spots (leukonychia);
- Contains natural actives.
- Unique Benefits of Nanovectores Encapsulation Technology
- Multifunctional Lipid Particles that promote hydration and extended effect
- Active Ingredient Protection against oxidation resulted from interaction with external environment and other components of the cosmetic formulation
- Monodispersity, that ensures control of the particle size, providing adequate permeation to its proposed action
- Secure particles larger than 200nm, biocompatible and biodegradable
- Enzymatic Specific Release Trigger, where enzymes present on the skin disintegrate particles, releasing the active ingredient specifically where it needs to act
- Greater Permeation on the contact surface due to the small size of the capsule
- Surface Charge Control of the particle, promoting greater affinity with the contact surface
- Water Base. Active ingredients are manufactured without the use of organic solvents, ensuring safety for users and the environment
- Encapsulated Active Ingredients Benefits
- Stability Improvement
- Use of sensitive active ingredients (without refrigeration)
- Increased Solubility
- Prolonged release
- Increased effectiveness
- Increased compability in the formulation
- Occlusion of odors
- Increased skin permeation
- Reduced dose
Applications & Uses
- Markets
- Applications
- Nail Care Applications
- Use level
- 1.0 - 25%
- Recommended Uses
Gel cream and liquid base
Properties
- Physical Form
- Odor
- Characteristic
- Appearance
- Milky liquid
- Typical Properties
- Physico-Chemical Properties
| Value | Units | Test Method / Conditions | |
| Relative Density | 0.9 - 1.1 | g/ml | — |
| Value | Units | Test Method / Conditions | |
| pH Value Stability | 4.0 - 8.0 | — | — |
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Efficacy Studies
Effectiveness Test
Test 1:
Product efficacy against leukonychia. Assessed product: Nano Nails 25% in cream base
Conclusion: The product had proven efficacy in the treatment of leukonychia in 61% of cases evaluated with effective improvement after 4 days of product applicationTest 2:
Reduction of nail streaks . Assessed product: Nano Nails 25% in nanostructured liquid base.
Conclusion: It was observed that after 7 days of use of the sample under study, there was significant reduction in flaking and whitish appearance of the skin in the nail folds (1), reducing roughness (2) and curls (3) of the nail plate, the latter, given by reducing the depth of the longitudinal streaks. Simulated 3D image was obtained by projection of roughness calculated in a rectangular area of the nail plate (2). Curls were obtained by profilometry curve obtained transversely to the nail plate.
Safety & Health
- Safety
The effectiveness of products for nails’ application is compromised by the complexity of the nail structure that makes it difficult for the actives to permeate. The technology developed and patented by Nanovetores, present in Nano Nails, favors the increased permeation
of the nanoencapsulated actives until the deeper layers of the nail plate, where the active will have an effective, safe and fast action.
Storage & Handling
- Storage and Handling
Keep in temperature between 20ºC - 25ºC