Knowde Enhanced TDS
Identification & Functionality
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
- Product Families
- Drug Type
- Drug type: basic drug molecular formula C4H11N5
Features & Benefits
- Physical and chemical properties
- Commonly used its hydrochloride, white crystal or crystalline powder; odorless. It is easily soluble in water, soluble in methanol, slightly soluble in ethanol, and insoluble in chloroform or ether. Its hydrochloride is commonly used as white crystal or crystalline powder; it is odorless. It is easily soluble in water, soluble in methanol, slightly soluble in ethanol, and insoluble in chloroform or ether.
Applications & Uses
- Applications
- Dosage Form
- Applications
- Mention of metformin dates back to the 1920s. It is a guanidine substance extracted from a plant called "goat bean". Metformin was officially used in clinical practice in 1957. Metformin is a class of "authoritative" drugs for the treatment of type 2 diabetes, and is listed as a first-line hypoglycemic drug in a variety of treatment guidelines at home and abroad. The drug has the advantages of precise hypoglycemic effect, low risk of hypoglycemia, and low price. It is currently one of the most widely used Class A hypoglycemic drugs.In recent years, with the deepening of research, in addition to the hypoglycemic effect of metformin, there are many surprising discoveries.
- Anti-aging effect: At present, the US Food and Drug Administration has approved the clinical trial of "using metformin to fight aging". The reason why foreign scientists use metformin as an anti-aging drug candidate may be because metformin can increase the release of metformin into cells. The number of oxygen molecules, logically speaking, seems to increase the body's strength and prolong life.
- Weight loss: Metformin is a hypoglycemic agent that can lose weight. It can increase insulin sensitivity and reduce fat synthesis. For many type 2 sugar lovers, weight loss itself is a thing that is conducive to stable control of blood sugar. A study by the United States Diabetes Prevention Program (DPP) research team showed that in an unblinded study period of 7-8 years, patients receiving metformin treatment lost an average of 3.1 kg in weight.
- Cardiovascular and cerebrovascular protection: Metformin has cardiovascular protection and is currently the only hypoglycemic drug recommended by the diabetes guidelines as having clear evidence of cardiovascular benefit. Studies have shown that long-term treatment of metformin is significantly related to the decreased risk of cardiovascular disease in newly diagnosed type 2 diabetic patients and type 2 diabetic patients who have already developed cardiovascular disease.
- Improve polycystic ovary syndrome: Polycystic ovary syndrome is a heterogeneous disease characterized by hyperandrogenism, ovarian dysfunction, and polycystic ovary morphology. Its pathogenesis is unclear, and patients often have varying degrees Hyperinsulinemia. Studies have shown that metformin can reduce insulin resistance, restore its ovulation function, and improve hyperandrogenemia.
- Anti-cancer and anti-tumor effects: In recent years, a number of epidemiological data have shown that metformin also has the effect of preventing and even treating tumors. Lung cancer is a disease that seriously endangers human health. It has a high incidence, a high case fatality rate, and a very poor prognosis. 86% of patients die within 5 years after diagnosis. More and more studies suggest that metformin can prevent lung cancer and improve the prognosis of lung cancer patients.
- Improve intestinal flora: Studies have shown that metformin can restore the proportion of intestinal flora and make it change in a direction that is beneficial to health. It provides an advantageous living environment for the beneficial bacteria in the intestines, thereby lowering blood sugar and positively regulating the immune system.
- It is expected to treat some autism: Recently, researchers at McGill University discovered that metformin can treat some forms of Fragile X syndrome of autism, and this innovative study was published in the sub-Journal Nature Medicine. In the magazine. At present, autism is one of many medical conditions that scientists believe can be treated with metformin.
Properties