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Micronised Purified Flavonoid Fraction

1 of 13 products in this brand
HTBA Micronised Purified Flavonoid Fraction is a flavonoid used as a venotonic for the chronic treatment of various cardiovascular conditions, such as CVD, varicose veins, hemorrhoids, spider veins, and heavy leg syndrome. It is a GMP-certified API that promotes blood circulation and addresses vascular discomfort. It is produced using a solvent-free method and complies with GMP standards.

Certifications & Compliance: DMF Type II, ECOVADIS, FAMI-QS, FSSC 22000, GMP, Halal, Hazard Analysis Critical Control Point (HACCP), ISO 14000, ISO 14001, ISO 9001, Kosher, SMETA-4, United States Pharmacopeia (USP), cGMP

Labeling Claims: Halal, Kosher, Solvent-free

Knowde Enhanced TDS

Identification & Functionality

Chemical Family

Features & Benefits

Applications & Uses

Properties

Physical Form
Appearance
Yellow to grey yellow inodorous powder
Insoluble in
Water, Methanol
Soluble in
1M sodium hydroxide, Dimethyl sulphoxide
Typical Properties
ValueUnitsTest Method / Conditions
Iodinemax. 0.1%
Watermax. 6.0%Karl Fischer
Sulphated ashmax. 0.2%
Microbiological Values
ValueUnitsTest Method / Conditions
Total Aerobic Microbial Countmax. 10³cfu/g
Total Yeast and Molds Countmax. 10²cfu/g
Enterobacteriaemax. 10²PNB/g
SalmonellaAbsence/g
Escherichia coliAbsence/g
Staphylococcus aureusAbsence/g
Particle Size Distribution
ValueUnitsTest Method / Conditions
Particles (smaller or equal than 10 μm)min. 90%
Impurities
ValueUnitsTest Method / Conditions
Any Impuritymax. 0.4%
Total Impuritiesmax. 1.3%
Flavonoids
ValueUnitsTest Method / Conditions
Diosmin87.0 - 93.0%
Hesperidin2.5 - 5.0%
Isorhoifolin0.9 - 2.8%
Linarin0.9 - 2.8%
Diosmetinmax. 2.0%
Total (other than diosmin)max. 13%
Total Flavonoids95.0 - 102.0%

Regulatory & Compliance

Technical Details & Test Data

Identification

A. Infrared absorption spectrophotometry. Comparison: Micronised Purified Flavonoid Fraction working standard.
B. Examine the chromatograms obtained in the assay.
Results: Main peaks in the chromatogram obtained with the test solution are similar in retention time and size to the mains in the chromatogram obtained with the Micronised Purified Flavonoid Fraction working standard solution.