- Chemical Name:Low-Substituted Hydroxypropyl Cellulose
- Functions:Binder, Disintegrant
- Dosage Form:Orally Disintegrating Tablets (ODTs), Tablets, Pellets
- Labeling Claims:Non-GMO, TSE-free, Allergen-free, Kosher, Solvent-free, BSE-free
- Certifications & Compliance:National Formulary (NF), United States Pharmacopeia (USP), DMF Type IV, European Pharmacopeia (Ph. Eur.), The Food Allergen Labeling & Consumer Protection Act of 2004 (FALCPA), GMP, Japan Pharmacopeia (JP), Kosher
L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.NBD Grades:Better flowability because of the non-fibrous particle shapeBetter compressibilityBetter tasteEnhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsA variety of grades are available depending on the application. L-HPC NBD-022 is suitable for direct compression and ODTs.