Products in Parenteral

NEOSORB® PF pyrogen-free sorbitol is used: as a carbohydrate source and osmotic diuretic agent in large-volume parenteral injectables as an isotonic agent for Rx injectables as an irrigating fluid for surgical procedures, to prevent intra- and extra-cellular dehydration

LYCADEX® PF is a pyrogen-free dextrose monohydrate that can be used: as isotonic agent in Rx excipients and in injectable applications including large volume parenteral, total parenteral nutrition as a carbohydrate source and osmotic agent for hemodialysis and peritoneal dialysis

PEARLITOL® PF is a pyrogen-free mannitol that is used for parenteral preparations and Rx injectables. Applications Osmotic diuretic agent in small and large volume parenteral injectables Isotonic agent and bulking agent for freeze-dried powder for Rx injection or infusion Pharmaceutical API used to reduce elevated pressure in the brain (cerebral oedema) and in the eyes (note: production has to comply with the internationally accepted GMP standards)

KLEPTOSE® HPB Oral Grade is a solubilizer and stabilizer for pharmaceutical and nutraceutical oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionary Syrups Suspensions Liquids Cream Paste Semi-solids Benefits Improves the solubility of poorly soluble compounds Can be used for taste masking of bitter or unpleasant active ingredients

KLEPTOSE® HPB Biopharma Hydroxypropyl Betadex Cyclodextrin is a low endotoxin grade materials that provides protein stabilization for biopharmaceutical downstream applications. With a hydrophobic internal cavity and hydrophilic exterior, KLEPTOSE® HPB BioPharma can encapsulate molecules, forming inclusion complexes where lipophilic compounds are non-covalently bound within the cavity. It is suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Benefits Unique ability to encapsulate and shield water insoluble materials can be utilized to shield exposed hydrophobic residues on aggregation-prone proteins, thereby modulating protein aggregation Shows promise as a multifunctional excipient suitable for biopharma applications Can serve as a tool to synergistically complement biotherapeutic formulations Multicompendial material (EP, USP, JP) Features Starch derivative Cyclic oligosaccharide with a bucket-like structure

KLEPTOSE® HPB Hydroxypropyl Betadex Cyclodextrin is a modified beta-cyclodextrin parenteral grade material that can be used as an encapsulating agent for Rx injectables. Benefits Improves stabilization of active substances against light and oxidation Enhances solubilization of active pharmaceutical ingredients Features White, amorphous powder Molecule is a torus-shaped ring with a polar hydrophilic outside and an apolar hydrophobic cavity

Kolliphor® P 188 micro Geismar is a versatile product that caters to healthcare and pharmaceutical applications, supporting various drug delivery methods like creams, dispersions, emulsions, foams, injectables, soft gels, and transdermal patches.

Kolliphor® EL, a versatile pharmaceutical ingredient, boasts PEG-35 castor oil as its key component. Functioning as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it finds applications in healthcare and pharma for drug delivery and care solutions. Ideal for ophthalmic, oral, parenteral, and topical applications, this liquid formulation seamlessly integrates into pharmaceutical and nutraceutical technologies. Offering a reliable solution across diverse domains, Kolliphor® EL stands out for its efficacy and adaptability in the realms of pharmaceuticals and nutraceuticals.

Kolliphor® HS 15, a polyethylene glycol-15-hydroxystearate, serves as a versatile surfactant, solubilizer, and emulsifier. Tailored for the pharmaceutical and nutraceutical industries, it finds applications in healthcare and pharma, specifically in drug delivery and care solutions. Well-suited for ophthalmic and parenteral applications, its physical form is a convenient paste. With its nonionic surfactant properties, Kolliphor® HS 15 contributes to enhanced formulation performance in the development of pharmaceutical and nutraceutical products.

Kollisolv® PYR, a liquid cosolvent, filler, and skin penetrant, primarily serves pharmaceutical and nutraceutical applications. Comprising 2-pyrrolidone, it excels in drug delivery and care solutions for both oral and parenteral use in healthcare and pharma. Its versatile nature makes it an ideal component in formulations, ensuring effective solubilization and enhanced skin permeation. With a focus on pharmaceutical technologies, Kollisolv® PYR stands out as a reliable choice for crafting efficient and innovative solutions for the healthcare industry.

Kolliphor® P 188 BIO, based on the chemical name poloxamer 188, serves as a versatile powder in pharmaceuticals and nutraceuticals. Its multifunctional capabilities include acting as a lubricant, solubilizer, surfactant, and emulsifier. Specifically designed for applications in healthcare and pharma, it excels in drug delivery and care solutions, especially in parenteral formulations. The physical form of this product is a convenient powder, making it easy to incorporate into various formulations within the pharmaceutical and nutraceutical industries.

Kolliphor® ELP is a versatile pharmaceutical excipient featuring PEG-35 castor oil. With its roles as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it plays a pivotal role in various pharmaceutical and nutraceutical applications. In healthcare and pharma, Kolliphor® ELP excels in drug delivery and care solutions, with applications in ophthalmic, oral, parenteral, and topical formulations. Presented in a convenient paste form, Kolliphor® ELP embodies cutting-edge technologies to meet the dynamic needs of the pharmaceutical industry.

Kollidon® 17 PF, a polyvinylpyrrolidone (PVP) belonging to pharmaceutical and nutraceutical technologies, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. This powder form excels in healthcare and pharmaceutical applications, specifically in drug delivery and care solutions for ophthalmic and parenteral uses. With its versatile properties, Kollidon® 17 PF ensures efficient performance in preventing crystallization, dispersing substances, enhancing solubility, acting as a solvent, and providing stabilization, making it an invaluable component in pharmaceutical formulations.

Kollidon® 12 PF is available in powder form, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. Positioned in the healthcare and pharma markets, it is suitable for injectables and carries the labeling claim of being pyrogen-free. Particularly applicable in ophthalmic and parenteral drug delivery and care solutions.

BTC Europe GmbH Dexpanthenol Ph.Eur. serves as an active pharmaceutical ingredient applicable for topical, oral, and injectable use. It demonstrates high hygroscopicity, enabling easy dissolution in water for producing liquid or semi-solid formulations. Dexpanthenol plays a vital role in enhancing wound healing, promoting epithelization, and exhibiting anti-inflammatory properties, thus finding application in local treatments. It is available in various dosage forms, such as spray, tablets, creams, ointments, eye drops, gels, syrups, capsules, soft gels, injectables, and foams, with health benefits emphasizing its anti-inflammatory attributes.

LACTEL® B6007-1 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6001-2 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6013-1 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6017-1 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6010-2 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6010-4 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6013-2 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6001-1 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6007-2 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6006-2 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6012-4 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6010-3 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6006-1 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

LACTEL® B6010-1 is a standard bioresorbable polymer commonly used in various application areas. In veterinary medicine, it is employed in long-acting injectable formulations. Additionally, it is utilized in human generic drug formulations, catering to price-sensitive planning and quick shipment requirements in fast-paced markets.It serves as a controlled release agent.

Omega-3-acid triglycerides (CN 600 TG) is a pale-yellow liquid comprised of a minimum of 30 per cent eicosapentaenoic acid (EPA) and a minimum of 20 per cent docosahexaenoic acid (DHA) presented as triglycerides (Ph. Eur. 1352 current ed.). The content of EPA and DHA triglycerides is a minimum 50 per cent and the content of total omega-3-acid triglycerides is a minimum 60 per cent. Tocopherol is added as an antioxidant. CN 600 TG is a concentrated and purified fish oil made from body oil of wild fatty fish. Alpha-tocopherol is added as antioxidant. No other additives. CN 600 TG is intended for use as an ingredient in finished formulations intended for parenteral use, for the supply of omega-3 fatty acids and energy when prescribed by a physician.

Kolliphor® ELP is a white to yellowish paste or cloudy liquid. It is a non-ionic solubilizer made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. This is followed by a purification process. Kolliphor® ELP forms clear solutions in water and also dissolves in a wide range of organic solvents, such as ethanol, n-propanol, isopropanol, ethyl acetate, chloroform, carbon tetrachloride, trichloroethylene, toluene and xylene.

Kolliphor® HS15 is a yellowish white paste at room temperature that becomes a liquid at approximately 30°C. It dissolves in water, ethanol and 2-propanol to form clear solutions. Its solubility in water decreases with increasing temperatures. It is insoluble in liquid paraffin.

Kolliphor® P 188 Micro Geismar is supplied as white to slightly yellowish microbeads. It is readily soluble in water and ethanol and other mainly polar solvents. It is insoluble in ether, paraffin and fatty oils.

Kolliphor® P 188 Bio is supplied as white to slightly yellowish, coarse grained powder with a waxy consistency. It is freely soluble in ethanol, freely soluble in water (opalescent solution), and is insoluble in diethyl ether, paraffin and fatty oils.

RESOMER® RG 752 H is a polymer offering various high and low molecular weights with different polymer compositions. This polymer can be carefully chosen to adjust degradation times. The RESOMER® polymers undergo solvent purification to achieve reduced residual monomer levels, ensuring high quality.It serves as a controlled release agent.

RESOMER® R 202 S is a polymer offering various high and low molecular weights with different polymer compositions. This polymer can be carefully chosen to adjust degradation times. The RESOMER® polymers undergo solvent purification to achieve reduced residual monomer levels, ensuring high quality.It serves as a controlled release agent.