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Amicogen AMK-EX

Amicogen AMK-EX produces D-CPC(deacetyl-cephalosporic C) from CPC(Cephalosporin C) or D-7-ACA(deacetyl-7-aminocephalosporanic acid) from 7-ACA(7-aminocephalosporanic acid).

Functions: Enzyme

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    Identification & Functionality

    Chemical Family

    Enzymes

    Pharma & Nutraceuticals Functions

    Enzyme

    Technologies

    Pharmaceuticals & Nutraceuticals

    Product Families

    Pharmaceuticals & Nutraceuticals — Excipients

    Formulation & Processing Aids

    Features & Benefits

    Characteristics
    • Very high specific activity
    • High substrate selectivity
    • High stability (reusable more than 800 cycles)
    • High production rate of D-CPC (more than 98%)
    • High production rate of D-7-ACA (more than 98%)​

    Applications & Uses

    Markets

    Healthcare & Pharma

    Applications

    Healthcare & Pharma — Pharmaceutical Manufacturing

    Pharmaceutical Processing

    Application
    • D-CPC production from CPC
    • D-7-ACA production from 7-ACA

    Properties

    Solvent
    Water
    Typical Properties
    ValueUnitsTest Method / Conditions
    pH7.9-8.0--
    Temperature20°C-
    Enzyme Amount7-10U/ml-
    Reaction Time1-1.5h-
    Activityᵃ (Wet Weight)300U/g-
    Size of Immobilization (min. 95%)150-300µm-
    Water Content 62%-
    Enzyme Assay

    aOne unit (U) represents the amount of enzyme required for producing 1μmol D-CPC and acetic acid per min in 50mM K-phosphate buffer containing 5% CPC, pH 8.0, at 25℃.

    Storage & Handling

    Storage
    • 4 - 10°C