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Amicogen AMK218

Amicogen AMK218 produces amoxicillin from 6-APA(6-aminopenicilanic acid) and HPGM(hydroxyphenylglycine methyl ester).

Functions: Enzyme

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    Identification & Functionality

    Chemical Family
    Pharma & Nutraceuticals Functions

    Features & Benefits

    Characteristics
    • Fast enzyme reaction
    • High stability (reusable more than 600 cycles)
    • High production rate of amoxicillin (more than 97.5%)​

    Applications & Uses

    Application

    Amoxicillin production from 6-APA and HPGM

    Properties

    Solvent
    Water
    Typical Properties
    ValueUnitsTest Method / Conditions
    pH6.2-6.3--
    Temperature10-20°C-
    6-APA:HPGM1:1.02-1.05--
    Enzyme Amount1:1-1.5U/ml-
    Activityᵃ (Wet Weight)100U/g-
    Size of Immobilization (min. 95%)250-300µm-
    Water Content 62%-
    Enzyme Assay

    aOne unit (U) represents the amount of enzyme required for producing 1μmol amoxicillin per min in 50mM K-phosphate buffer containing 30mM
    6-APA(6-aminopenicilanic acid) and 30mM HPGM(hydroxyphenylglycine methyl ester), pH 6.1, at 28℃.

    Storage & Handling

    Storage
    • 4 - 10°C