Knowde Enhanced TDS
Identification & Functionality
- Product Type
- Technologies
- Product Families
Features & Benefits
- Labeling Claims
- Ready-to-Use Product Features
- Features & Benefits
- Effective: RepelaCOAT prevents growth of commonly occurring organisms such as E.coli, S.aureus, and P.aeruginosa.
- Safe: RepelaCOAT maintains a slow release profile that minimizes toxicity to surrounding tissue.
- Long Lasting: RepelaCOAT has demonstrated effectiveness for up to 30 days.
- Aqueous: RepelaCOAT coatings, since they are based on the LubriLASTTM platform, contain no organic solvents. Safer and cleaner manufacturing processes are used and any concerns about residual solvents in a device are eliminated.
- Durable: RepelaCOAT retains its physical integrity even after hundreds of cycles.
- Lubricious: RepelaCOAT incorporates lubricious polymers that reduce patient trauma and increase ease of handling.
Applications & Uses
- Markets
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- How does RepelaCOAT work?
In RepelaCOAT, silver salts and/or antibiotics are ionically bonded to the supporting polymer. In the presence of the sodium or calcium ions characteristic of body fluids, the antimicrobial agents ion exchange with these physiological cations. Long chain hydrophilic polymers incorporated in the coating adsorb water molecules and facilitate the ion exchange. Rather than exhibiting a huge “spike” of activity that diminishes rapidly over time - and that may be toxic to the surrounding tissues - RepelaCOAT prevents bacterial adherence by its slow ion-exchange release of anti-microbial agents.
- Anti-Microbial Coating
RepelaCOAT is an infection-resistant medical device coating with a patent pending, ion-exchange release mechanism. Unlike most anti-microbial coatings that have only a brief, initial spike of activity, RepelaCOAT can be customized to have a controlled, initial “peak release” followed by a sustained release of anti-microbial agents in the presence of blood or urine.
- Anti-Microbial Profile — Silver Salt
- Anti-Microbial Profile — Antibiotic
