Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 84012-27-1
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Highlights
- Antioxidant
- Protective
- Antimicrobial
- Tone unifier
Applications & Uses
- Markets
- Applications
- Application Format
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.2 - 0.5
Properties
- Physical Form
- Appearance
- Liquid
- Physico-Chemical Properties
- Microbiological Values
- Heavy Metals
| Value | Units | Test Method / Conditions | |
| Humidity | max. 40 | % | Karl Fischer |
| Ash Content (3h 800°C) | max. 15 | % | - |
| Hydroxytyrosol (HTy) | min. 25 | % | HPLC Absolute value, HTy standard |
| Value | Units | Test Method / Conditions | |
| Total Plate Count | max. 1000 | cfu/g | PNT - 005 |
| Yeast & Mold Count | max. 100 | cfu/g | PNT - 005 |
| Escherichia Coli | Negative | - | PNT - 005 |
| Coliforms | Negative | - | PNT - 005 |
| Staphylococcus Aureus | Negative | - | PNT - 005 |
| Salmonella Spp | Negative | - | PNT - 005 |
| Value | Units | Test Method / Conditions | |
| Heavy Metals | max. 10 | ppm | Turbidimetria |
| Lead | max. 3 | ppm | ICP / MS |
| Arsenic | max. 2 | ppm | ICP / MS |
| Cadmium | max. 1 | ppm | ICP / MS |
| Mercury | max. 0.1 | ppm | ICP / MS |
Technical Details & Test Data
- Antioxidant Test
- DPPH test is the method to measure the ability of compounds to act as free radical scavengers and to evaluate the ANTIOXIDANT activity.
- HYDROXYTYROSOL shows a higher ANTIOXIDANT activity than Q10 and IDEBENONE.
- HYDROXYTYROSOL shows an antioxidant efficacy very similar to vitamin C but without the stability problems found in vitamin C.
- Antioxidant Capacity : ORAC Test
- Assessment of the ANTIOXIDANT capacity by the ORAC method. The results expressed in Umol/mg.
- As a comparison product, the same titration was carried out with ASCORBIC ACID.
- Oxidative Stress Test - Ageless
- The ACTIVITY of the β- galactosidase decreases depending on the INCREASE in the concentration of HYDROXYTHROSOL.
- Therefore, these TESTS confirm that HYDROXYTHROSOL reduces oxidative stress in aging cells to subsequently INHIBIT the progression of AGING.
- Anti Inflammatory Test
The study examined changes in IL-1β, IL-6, and IL-8 gene expression when treating UV-aged human dermal fibroblast with HYDROXYTYROSOL at different concentrations to identify the ANTI-INFLAMMATORY effects of hydroxytyrosol.
The expressions of the genes of IL-1β, IL-6 and IL-8 decreased as the concentration of HYDROXYTYROSOL increased. The results show the anti-inflammatory effects of hydroxytyrosol on human dermal fibroblasts (HDF) damaged by UVA rays.
- Sun Protector Test
The PROTECTIVE effect of HYDROXYTYROSOL against UVB- induced DNA damage was investigated in a human skin keratinocyte cell line, HaCaT. The assay was used to monitor DNA strand breaks.
The results showed that HIDROXYTYROSOL significantly reduced DNA strand breaks caused by UVB.
- Anti-Stain Test
HYDROXYTYROSOL increases the antioxidant power of the skin by increasing the amount of glutathione in the cells. A higher amount of glutathione also directs melanin production towards the lighter and more soluble pheomelanin. HYDROXYTYROSOL significantly lightens skin color by reducing overall melanin production.
The test shows that HYDROXYTYROSOL is capable of significantly reducing the content of MELANIN in primary human melanocytes in the range between 0.002 - 0.008%.
Test
- Dry Skin, Volunteer 49 Years
- 12 Weeks of Cream Application with 0.2% Olive Extract 2 Times a Day
Packaging & Availability
- Packaging
- 5 Kg Jerrycan
Storage & Handling
- Shelf Life
- 24 months
- Other Information
- In case of possible long storage, it’s recommended to keep it under cold conditions (2-4°C)