Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Ingredient Name
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
- Ingredients
- Terminalia Arjuna
Features & Benefits
- Benefit Claims (Health)
- Labeling Claims
- Product Highlights
- Cardiovascular disease (CVD) is a leading cause of mortality and is responsible for the deaths of 17 million people each year, approximately one-third of all global deaths annually. Of the estimated 16.6 million deaths attributed to CVD worldwide, 80% is in developing countries. About 75% of the mortality among diabetic men, and 57% among diabetic women, is attributed to cardiovascular disease. Higher concentrations of Low Density Lipoprotein (LDL) and lower concentrations of functional High Density Lipoprotein (HDL) have been found to be associated with cardiovascular disease as these promote atherosclerosis, leading to myocardial infarction and stroke. As a first line of intervention as well as during treatment conditions with cholesterol reducing drugs, changes to the lifestyle are recommended. In the recent past functional foods fortified with plant based bioactives and dietary supplements have found increasing focus as adjuvant in cholesterol management.
- SmartcholTM has been reducing cholestrol and triglycerides, thereby managing cardio vascular health
Applications & Uses
- Markets
Technical Details & Test Data
- Scientific Perspectives
SmartCholTM has shown efficacy in cholesterol management and has been thoroughly characterized using metabolite fingerprinting and by testing physical and chemical safety parameters. Animal studies on Hypercholesterolemic Sprague dawley rats have shown SmartCholTM is efficacious in lowering plasma triglyceride and total cholesterol while increased HDL-Cholesterol at concentration of 100 mg/kg body weight. The safety and toxicity studies showed that SmartCholTM is non-toxic to rats at dose levels of 2000 mg/kg body weight and 5000 mg/kg body weight. Therefore, the LD50 of SmartCholTM is expected to exceed 5000 mg/kg body weight. Safety and Efficacy studies have proven SmartCholTM as potential lead in Dyslipidemia management.
SmartcholTM - Developmental Strategy
