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Bachem EXENATIDE ACETATE

Bachem EXENATIDE ACETATE is a 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon.

Chemical Name: Exendin 3 (Heloderma horridum), 2-glycine-3-L-glutamic acid-

Certifications & Compliance: DMF Type I, cGMP

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Knowde Enhanced TDS

Identification & Functionality

Molecular formula
C184H282N50O60S
CAS No.
141758-74-9
EC No.
686-356-3
Sequence

H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt.

Applications & Uses

Fields of Application

Diabetes II

Properties

Typical Properties
ValueUnitsTest Method / Conditions
Relative Molecular Mass4186.63g/mol-

Regulatory & Compliance

Certifications & Compliance
Bachem Regulatory Documentation

DMF

Storage & Handling

Long-term Storage

-20 ± 5 °C