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Bonolive® is a patented olive leaf extract designed to support post-menopausal women and address concerns such as loss of bone mass, joint discomfort, and blood lipids disbalance.



Bonolive® is standardized for highly bioavailable oleuropein (>40%), a powerful phytonutrient unique to the olive tree.



At the cellular level, Bonolive® promotes bone formation by inhibiting adipocyte differentiation and enhancing differentiation into osteoblasts, the bone-building cells.



Additionally, Bonolive® reduces levels of inflammation and cartilage degradation biomarkers, such as PGE-2 and collagen-II, that are involved in the process.



Three clinical studies support bonolive® efficacy. A daily dose of 250 mg of Bonolive® results in the following health benefits:



  • Increases bone metabolism biomarker osteocalcin by 32%
  • Protects against loss of bone mass density
  • Reduces joint pain
  • Improves joints mobility
  • Improves blood lipid profile



Bonolive® is water-soluble and has shown excellent bioavailability in humans. It can be formulated in various dietary supplement forms, including capsules, sachets, tablets, chewable, gummies, shots and shelf-stable drinks.



Key applications:



  • Post-menopausal women's health
  • Osteopenia, osteoporosis, and bone health support
  • Osteoarthritis and joint health

Ingredient Name: Olive Leaf Extract

Active Component: Oleuropein

Functions: Phytochemical

Physical Form: Powder, Solid

Benefit Claims (Health): Joint Support, Pain Reduction, Supports Menopause Health

Features: Excellent Bioavailability, Improved Bone Health, Promotes Joint Comfort And Mobility, Supports Healthy Joints

    Knowde Enhanced TDS

    Identification & Functionality

    Active Component
    Country of Origin
    Ingredient Name
    Pharma & Nutraceuticals Functions
    Ingredients
    Olive Leaf Extract

    Features & Benefits

    Applications & Uses

    Properties

    Physical Form
    Appearance
    Green to brown powder
    Typical Properties
    ValueUnitsTest Method / Conditions
    Extraction SolventWater/Alcohol
    Raw Material/Extract Ratio12-15 : 1
    Polycyclic Aromatic Hydrocarbons (PAH)
    ValueUnitsTest Method / Conditions
    Benzo(a)Pyrenemax. 10ppb
    Sum of Benzo(a)Pyrene, Benz(a)Anthracene, Benzo(B)Fluoranthene and Chrysenemax. 50ppb
    Additional Information
    ValueUnitsTest Method / Conditions
    Pesticides**According To Regulation EC (396/2005)
    Ethylene Oxidemax. 0.02ppm
    Physico-Chemical Properties
    ValueUnitsTest Method / Conditions
    Loss on Dryingmax. 8.0%
    Residue By Calcinationmax. 9.0%
    Microbiological Values
    ValueUnitsTest Method / Conditions
    Total Plate Countmax. 10^{3}cfu/g
    Yeast & Moldmax. 10^{2}cfu/g
    Enterobacteriaceaemax. 10^{2}cfu/g
    SalmonellaAbsence/25g
    Escherichia ColiAbsence/g
    Staphylococcus AureusAbsence/g
    ColiformsAbsence/g
    Nutritional Information
    ValueUnitsTest Method / Conditions
    Nutritional Value (Calculated)381.3kCal/100g
    Total Fat Content0.3g/100g
    Saturated Fatty Acids56.4%
    Total Carbohydrates94.4g/100g
    Assimilable Carbohydrates93.1g/100g
    Total Sugar (As Glucose)4.2g/100g
    Total Fibers1.3g/100g
    Total Protein0.9g/100g
    Sodium62.7mg/100g
    Assay
    ValueUnitsTest Method / Conditions
    Polyphenolsmin. 50%HPLC (Internal method)
    Oleuropeinmin. 40%HPLC (Internal method)
    Verbascosidemin. 0.5%HPLC (Internal method)
    Residual Solvents
    ValueUnitsTest Method / Conditions
    Residual SolventsEthanol And Water
    Heavy Metals
    ValueUnitsTest Method / Conditions
    Leadmax. 3ppm
    Cadmiummax. 1ppm
    Mercurymax. 0.1ppm
    Arsenicmax. 2.0ppm
    Note
    • *Analyzed at least one batch a year
    • ** Analyzed at raw material level
    Solubility
    Forms stable homogenous suspension when dispersed in water at 1 gram : 1 gram ratio

    Regulatory & Compliance

    Storage & Handling

    Shelf Life
    3 years
    Storage & Shelf Life
    • Storage: Keep in tight containers to prevent dust formation. Store in a dry and cool place, away from direct sunlight. Keep away from ignition, heat, or electricity sources
    • Retesting date: 3 years after the date of production (when stored under the described conditions)