Knowde Enhanced TDS
Identification & Functionality
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
Features & Benefits
- Benefit Claims (Health)
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Applications & Uses
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Properties
Technical Details & Test Data
- Psychopharmacological Activity
- The composition of COGNITYL has been inspired by Smit's experiments.
- Smit et al. have proven in a clinical trial in 2004 that an oral dose of 250 mg of theobromine and 19 mg of caffeine helps people to concentrate, feel energetic, and develop a feeling of well-being and pleasure.
- In 2004, the effects of cocoa constituents (caffeine and theobromine) were tested on mood and performance and the activity compared to that of the same amount of xanthines found in cocoa powder and to placebo.
- The profile of effects of cocoa powder with methylxanthines and the methylxanthines alone were found to be identical: an increase in energetic arousal and hedonic tone, performance improvements on simple reaction time and information processing, all this compared to placebo.
- With this study, it was concluded that theobromine and caffeine were responsible for the psychopharmacological activity of chocolate.
- Cognityl Is Delivered With a Complete Package of Information, Including Bioxtract Proprietary
- Pre-clinical acute oral toxicity trial in rats showing no particular effect and classifying the product in the danger 5 category DL50 superior 5,000 mg/kg.
- Bibliographical Phase II clinical trial showing results obtained with identical ratio and concentration in caffeine and theobromine.