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Chengdu Jinkai Biology Engineering Kojic acid

Chengdu Jinkai Biology Engineering Kojic Acid, (formal name: 5-hydroxy-2-hydroxymethyl-1,4-pyrone) is a kind of sub acid organic compound made in microbial fermentation. Kojic acid is white or off-white needle-like crystals, easily dissolved in water, alcohol and acetone. It is slightly dissolved in ether, ethyl acetate, chloroform and pyridine and undissolved in benzene.

Chemical Name: Kojic Acid

Functions: Skin Protectant

Dosage Form: Ointments

    Knowde Enhanced TDS

    Identification & Functionality

    Chemical Name
    Ingredient Origin
    Pharma & Nutraceuticals Functions
    CAS No.
    501-30-4
    Molecular formula
    C6H6O4
    EC No.
    207-922-4

    Applications & Uses

    Dosage Form
    Usage
    1. Application in cosmetic field: It is used for macula-removing and whitening.In the human skin, tyrosine is oxidized and polymerized with oxygen-derived free radicals under the catalytic action of tyrosinase and then synthesized to melanin. Kojic acid can inhibit tyrosinase synthesis, so it can greatly inhibit the skin melanin formation; furthermore, kojic acid is safe and nontoxic and wont cause white spot syndrome. Therefore, it has been widely added in the lotion, face mask, liquid cream and skin cream. Whitening cosmetics containing kojic acid are able to treat effectively the freckle, senile plaque, pigmentation and acne, etc. Kojic acid in concentration of 20ug/ml is able to inhibit 70~80%of the activity of many kinds of tyrosinases (or polyphenoloxidase PPO) . 0.2~1.0% of kojic acid is recommended to be added in the cosmetics.
    2. Moreover, kojic acid is the mateial for making maltol and cthyl maltol.
    3. In medicine field: kojic acid has no mutagenic action to eukaryotic cells. It is able to eliminate the free radicals in the human body, strengthen the activity of the leucocyte, so it is good for human health. Now kojic acid has been used as the an important material of cephalosporin-type antibiotics. The finished products have ideal effect in easing pain, relieving inflammation and curing many diseases (like headache and toothache, etc.).
    4. In agriculture field: Kojic acid is used in producing biological pesticides. 0.5-1.0% of kojic acid can be added in microelement fertilizer (crimson liquid). This kind of crop production promoter has significant effect on increasing production of grains and vegetables, no matter it is used as low-concentration foliage fertilizer for spraying or yield-increasing agent for root applying.
    5. In other fields: kojic acid is also used as iron analytical reagent and film spotting agent, etc.

    Properties

    Appearance
    White or off-white needle-like crystals
    Typical Properties
    ValueUnitsTest Method / Conditions
    Molecular Weight142.1
    Melting Point153-156°C
    Puritymin. 99.0%
    Residue On Ignitionmax. 0.1%
    Iron Contentmax. 10ppm
    Chloride Contentmax. 50ppm
    Heavy Metal Contentmax. 3ppm
    Arsenic Contentmax. 1ppm
    PathogensNone/undetected
    DissolubilityEasily dissolves in water, colorless and transparent

    Safety & Health

    Safety

    Notice: If splashed in the mouth or eyes, flush thoroughly with clean water.

    Packaging & Availability

    Packaging

    25kg of kojic acid per bag (inner-plastic and outer-aluminum foil bag), cardboard drum for external packing, make according to the clients requirements.

    Storage & Handling

    Storage

    Keep it in a ventilated and dry place, prevent from sunligh.Guarantee period of 3 years.