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CLR Berlin GmbH is a leading manufacturer of innovative, high-quality, natural and safe products for skin and hair care ingredients for the international cosmetics industry. With more than 80 years of comprehensive research, development, responsible manufacturing and fair business practices, we have earned the trust of customers all over the world. Our integrated management system combines both quality and environmental aspects in accordance with ISO 9001 and ISO 14001 standards.

ProBioBalance CLR™ NP

ProRenew Complex CLR™

Belides™ ORG

JuvenEye CLR™

MultiMoist CLR™

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MultiMoist CLR™ is a natural, plant-derived active ingredient addressing short and long term skin hydration. While aiming for a high level of hydration in the outer layers of the skin, the Stratum Corneum (SC), it also stimulates the expression of the Vitamin D Receptor. MultiMoist CLR™ is a unique non-preserved aqueous complex at its highest possible concentration.

MultiMoist CLR

Soluvit  is suitable for a wide variety of skin and haircare concepts, such as the treatment of eye bags, dark circles, bruises and the care of tired legs and nails, but also for anti–hair loss. Soluvit  is based on an extract of horse chestnut enriched with vitamins A, E, F, H (biotin) and vitamins of the B group. Horse chestnut has a rich history of use in traditional and modern medicine, especially for its stimulating and energizing properties. The vitamins show an extensive range of potential benefits for both skin and hair.


Soluvit

Belides™  is a natural skin-lightening agent, derived from organic daisy flowers (Bellis perennis). It is suitable for any skincare concept providing even and luminous complexion and radiant skin. Belides™  action is based on a potent, multifaceted reduction in the activity of melanocytes. Belides™ influences different cellular pathways involved in melanogenesis, encompassing the reduction of cellular signaling, tyrosinase transcription, tyrosinase activity and melanosome transfer. These actions lead to even pigmentation and make age spots less visible.

Belides

SyriCalm™ is a natural product derived from Poria cocos and Phragmites. It effectively reduces inflammation and strongly supports skin in dealing with external stresses. Additionally, SyriCalm™ is designed to give effective support where the skin is challenged by environmental stress, e.g. shaving, depilation or daily hygiene. It helps the skin recover its natural balance.

SyriCalm

Repair Complex CLR™ PF is a biotechnological anti-aging active, obtained from a lysate of probiotic bifidobacteria, which potently protects against UV-induced damage in the skin. UV radiation leads to skin cell damage and immunosuppression, a deactivation of the local immune system in the skin. By effectively activating anti-immunosuppressive processes on the cellular level, Repair Complex CLR™ PF increases cellular repair and potently supports the skin’s endogenous protection mechanisms. Repair Complex CLR™ PF thus counteracts premature skin aging, i.e. photoaging.


Repair Complex CLR

Hygroplex™ HHG is a physiological moisturizer, specifically designed to be fully adapted to the water-binding capacity of human skin, containing ingredients similar to the Natural Moisturizing Factors (NMF) in the skin. It is extremely suitable for skincare concepts for dry and aged skin and can be used in any skincare application for any type of skin which needs hydration. Hygroplex™ HHG effectively moisturizes and smoothes the skin. Additionally, it has shown to be a potent moisturizer for hair, increasing its water content and improving its mechanical properties.

Hygroplex

AnnonaSense CLR™ provides the skin with means to establish a sustainable homeostatic balance, improving skin health and well-being. The potent adaptogenic action of AnnonaSense CLR™ supports the skin’s endocannabinoid system by activating the CB2 receptor. Through this action, it reduces inflammatory processes induced by TRPV1. Histamine-, as well as TNFα / Substance P-induced stress is down-regulated and the expression of a vital detrimental receptor in skin, IL-31RA, is decreased. AnnonaSense CLR™ makes the skin less sensitive and more balanced, even itch is perceivably reduced. Skin appearance is improved and the perception of well-being and quality of life is enhanced. AnnonaSense CLR™ is obtained from Annona Cherimola, common name Cherimoya, an edible fruit originating from South America.

AnnonaSense CLR

Sedaplant™  is applicable in a wide variety of skin and haircare concepts, such as baby care, and care for sensitive skin and scalp. Sedaplant™  contains potent mixtures of extracts from fennel, hops, chamomile, balm mint, mistletoe, yarrow, urea and allantoin. All ingredients are well known and well appreciated in both traditional medicine and modern science, especially for their skin-healing and soothing properties.

Sedaplant

PhytoDefense CLR™ is carefully designed for the care of hyper-reactive and irritable skin. It essentially reduces the sensitivity of skin by its goal-oriented approach to the most important features of sensitive skin: burning/stinging/itching sensations and skin redness. Skin irritations as well as skin redness are noticeably reduced. PhytoDefense ™ is obtained from Magnolia grandiflora, known in traditional medicine for its potent calming and soothing properties.


PhytoDefense CLR

Follicusan™ DP stimulates the functionality of the dermal papilla cells at the base of the hair follicles, thus counteracting premature hair loss. It increases the number of anagen hair follicles (growth stage) and decreases that of telogen hair follicles (resting stage). Hair density as well as cumulative hair thickness is increased. Follicusan™ DP contains biologically active signaling proteins, ethyl panthenol (provitamin B5), inositol as well as acetyl cysteine and acetyl methionine in a water-ethanol medium.

Follicusan™ DP

Repair Complex CLR™ PF is a biotechnological anti-aging active, obtained from a lysate of probiotic bifidobacteria, which potently protects against UV-induced damage in the skin. UV radiation leads to skin cell damage and immunosuppression, a deactivation of the local immune system in the skin. By effectively activating anti-immunosuppressive processes on the cellular level, Repair Complex CLR™ PF increases cellular repair and potently supports the skin’s endogenous protection mechanisms. Repair Complex CLR™ PF thus counteracts premature skin aging, i. e. Photoaging.

Repair Complex CLR™ PF

Belides™ ORG is a natural skin-lightening agent, derived from organic daisy flowers (Bellis perennis). It is suitable for any skincare concept providing even and luminous complexion and radiant skin. Belides™ ORG’s action is based on a potent, multifaceted reduction in the activity of melanocytes. Belides™ ORG influences different cellular pathways involved in melanogenesis, encompassing the reduction of cellular signaling, tyrosinase transcription, tyrosinase activity and melanosome transfer. These actions lead to even pigmentation and make age spots less visible.

MPC™ reduces the visible signs of aging by reactivating skin cells and inducing the production of extracellular matrix molecules in the dermis, such as collagen Type I, hyaluronic acid and fibronectin. In vivo studies have shown that formulations with MPC™ make the skin firmer and improve its elasticity. MPC™ quickly and effectively reduces wrinkle depth and improves the structure of the skin. MPC™–Milk Peptide Complex contains a complex of activated, natural signaling growth factors derived from milk, such as TGF-β. Also available encapsulated in plant-derived liposomes as MPC™-Liposomes.

MPC™ Milk Peptide Complex

Vitamin F forte nurtures, protects and acts as a skin conditioner. It is particularly suitable for the treatment of dry, stressed and sensitive skin, potently supporting the skin in rebuilding and maintaining its natural healthy structure and functionality. Vitamin F forte also has some great benefits for hair. Vitamin F forte contains natural polyunsaturated essential free fatty acids originating from safflower oil, with a particularly high content of linoleic acid.

Vitamin F Forte

DayMoist CLR™ potently and immediately increases the concentration of the natural moisturizing factors (NMF) in the upper layers of the skin, resulting in immediate and long-lasting moisturizing effects. These results were obtained by making use of Confocal Raman Microspectroscopy and analyzing skin capacitance. Additionally, DayMoist CLR™ has potent hair care properties. DayMoist CLR™ is a complex of natural plant-derived active ingredients.

DayMoist CLR™

Hexaplant™ Richter is applicable in a wide variety of skin and haircare concepts, such as baby care, and care for sensitive skin and scalp. Hexaplant™ Richter contains potent mixtures of extracts from fennel, hops, chamomile, balm mint, mistletoe and yarrow. All ingredients are well known and well appreciated in both traditional medicine and modern science, especially for their skin-healing and soothing properties.

Hexaplant™ Richter

Soluvit Richter NP is suitable for a wide variety of skin and haircare concepts, such as the treatment of eye bags, dark circles, bruises and the care of tired legs and nails, but also for anti–hair loss. Soluvit Richter NP is based on an extract of horse chestnut enriched with vitamins A, E, F, H (biotin) and vitamins of the B group. Horse chestnut has a rich history of use in traditional and modern medicine, especially for its stimulating and energizing properties. The vitamins show an extensive range of potential benefits for both skin and hair.

Soluvit Richter NP

ProBioBalance CLR™ NP activates cellular processes involved in cellular nutrition and helps activate detoxification processes. The metabolic activity of skin cells is increased, and the skin’s immune system strengthened and protected against environmental stress. The application of ProBioBalance CLR™ NP leads to reduction of skin inflammation and also actively prepares skin for external stresses. ProBioBalance CLR™ NP consists of probiotic bifido cultures which are suspended and disintegrated in a biologically active milk-based matrix.

CLR Berlin GmbH

CLR Berlin GmbH is a leading manufacturer of innovative, high-quality, natural and safe products for skin and hair care ingredients for the international cosmetics industry. With more than 80 years of

CLR Berlin GmbH - Knowde

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Modukine™ Safety Data Sheet

Modukine™ Safety Data Sheet - CLR Berlin GmbH - Knowde

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