Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
Features & Benefits
- Benefit Claims
Applications & Uses
- Markets
- Color Cosmetic Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.5-5%
- Mode Of Action
Commonly known as vitamin A, this term includes both retinol and its esters which can be transformed into retinal and retinoic acid by metabolic processes. Plants contain no vitamin A, only carotenoids – or provitamin A - which can be converted into retinol in the human or animal organism.
Vitamin A plays an important part in building up the skin. This has become evident by demonstrating its stimulating effects on the one hand and by analyzing the consequences of vitamin A deficiency on the other. For example, vitamin A has been found to stimulate cell growth and act as a survival factor for fibroblasts in vitro. The growth-stimulating effect of vitamin A is based on different mechanisms: Cell replication is stimulated, binding of `epidermal growth factor´ is increased and secretion of `human growth hormone´ is induced. Vitamin A stimulates sebaceous gland activity, but does not cause excess secretion. Retinoic acid receptor inhibition has been found to disrupt the epidermal barrier function. In addition, vitamin A deficiency increases inflammatory responses. In contrast, topical application of retinol has been found to enhance stratum corneum response to environmental threat.
There are different mechanisms to ensure that the cells are sufficiently supplied with retinol and retinoic acid. Keratinocytes, for example, are able to take up and esterify both free retinol and retinol bound to retinol-binding protein. Keratinocytes of the upper skin layers use retinol that has formed through hydrolysis of retinyl esters in differentiating basal keratinocytes. In the epidermal basal layer, retinol is oxidized to form retinoic acid. Only retinoic acid can cause upregulation of elastin expression.
- Recommended Uses
- Preparations with Carrot Oil CLR are likewise suitable for application to dry, cracked and scaling skin and scalp, and for the preventive care of hair.
- Carrot Oil can be used in emulsified and oily skin and hair care preparations.
- Processing
Due to the natural character of the product slight turbidity might occur at temperatures below approx. 20°C.
Carrot Oil CLR may be briefly heated to the temperatures required for the manufacture of emulsified preparations.
Since provitamin A is decomposed in acid solutions, Carrot Oil CLR should not be combined with, for example, free fatty acids (vitamin F). On the other hand there is no objection to processing Carrot Oil CLR in conjunction with fatty acid esters (vitamin F esters).
Cosmetics with Carrot Oil CLR have a reddish (skin oils) to yellow (creams, liquid emulsions) tinge.
Properties
- Physical Form
- Odor
- Slight characteristic
- Appearance
- Dark-red Oil
- Insoluble in
- Water
Regulatory & Compliance
- Certifications & Compliance
Safety & Health
- Physiological Safety
Acute oral toxicity
LD50 oral: min. 5 ml/kg bodyweight (rat).
Carrot Oil CLR is hence to be designated as non-toxic.
Eye irritation potential
Carrot Oil CLR has undergone the Draize test. There is no objection to the application of Carrot Oil CLR in the vicinity of the eyes.
Skin tolerance
Carrot Oil CLR has been used in cosmetic preparations for many years: No negative effects are known.
Packaging & Availability
- Packaging Information
- Pack size: 5 kg, 25 kg
- Sample size: 50 g
Storage & Handling
- Storage and Handling
Storage at cellar to room temperature (15-25°C), in well-closed containers, protected from light. Product packs should be fully used once opened. Under these conditions Carrot Oil CLR is stable for at least 1 year.
Temperatures clearly falling below recommended storage temperature have to be avoided because non-reversible crystallization could occur.