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CutiBiome CLR™

1 of 1 products in this brand
CutiBiome CLR™ is a synergistic complex of lipophilic extracts from Manuka, Black Pepper and Magnolia. It provides essential support for the natural balance between skin and its microbiota in difficult situations, like acne and dandruff. CutiBiome CLR™ reduces the film forming activity and significantly inhibits the growth of virulent phylotypes of Cutibacterium acnes. It strongly reduces inflammation involved in acne and dandruff. Sebum, comedones, pustules and pimples are reduced dramatically, as was confirmed by instrumental determinations and the volunteers themselves. Other in vivo studies showed potent reduction of dandruff. 4 weeks of 3 times weekly use of a hair tonic with CutiBiome CLR™ lead to similar results to Piroctone Olamine, but clearly outperformed it in reducing scalp oiliness, sensitivity and itch.

INCI Name: Leptospermum Scoparium Branch/Leaf Oil, Magnolia Officinalis Bark Extract, Octyldodecanol, Piper Nigrum (Pepper) Fruit Extract

Functions: Anti-Dandruff Agent, Anti-Inflammatory, Sebum Regulator

Ingredient Origin: Natural Origin, Plant Origin

Labeling Claims: Natural, Naturally Derived, Ulta Beauty's Conscious Beauty

Certifications & Compliance: COSMOS

Benefit Claims: Anti-Acne, Anti-Dandruff, Anti-Inflammatory, Calming, Sebum Control, Soothing, Stress Reducing

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Identification & Functionality

Features & Benefits

Applications & Uses

Application Format
Hair Care Applications
Treatment Product Applications
Use Level
1.5 - 3.0 %
Recommended Uses

CutiBiome CLR is intended for usage in both skin and scalp care formulations. Preferred applications are usage in formulations for oily or mixed skin with a poor complexion, impure or partly inflamed skin (incl. acne skin). It has also shown to have a potent regulating effect on elevated sebum production. CutiBiome CLR can easily be incorporated in emulsified skin and hair/scalp care preparations, lotions or serums.

Formulations Guidelines

CutiBiome CLR can be added to the formulation until temperatures of 95°C. Simple mixing of the formulation should be sufficient to homogeneously distribute CutiBiome CLR in the bulk.

Properties

Physical Form
Odor
Weak specific
Appearance
Yellowish oily liquid
Physical Properties
ValueUnitsTest Method / Conditions
Density (20°C)0.840 – 0.850g/ml
Refractive index nD201.450 – 1.460
Color Value0 – 6Gardner
pH4.0 - 7.0

Regulatory & Compliance

Certifications & Compliance

Safety & Health

Physiological Safety

Acute oral toxicity
CutiBiome CLR contains ingredients, which have a long tradition in plant medicine. CutiBiome CLR is considered to be non-toxic and safe in cosmetic use at the levels advised by us.


Eye irritation potential
CutiBiome CLR (undiluted) was tested on the chorioallantoic membrane of the hen's egg where it produced an irritation index of 0.00 and was classified as "non-irritant" to mucous membranes.


CutiBiome CLR (undiluted) was tested using the Bovine Corneal Opacity and Permeability Assay (BCOP). The calculated mean in vitro irritation score was 1.64. According to the evaluation criteria CutiBiome CLR is classified into UN GHS “No Category”.


Skin tolerance
A 48 hour patch test on 50 volunteers has been performed using CutiBiome CLR (undiluted), among these 26 individuals with normal skin, 5 sufferers from eczema, 4 allergic and 15 individuals with sensitive skin. This test showed neither skin irritant nor sensitizing effects. Thus CutiBiome CLR can be classified as harmless as regards the possibility of skin irritation.

Mutagenicity
CutiBiome CLR was investigated for its potential to induce gene mutations according to the bacterial reverse mutation assay using 4 different strains of Salmonella typhimurium and E. coli WP2 uvrA bacteria, with and without metabolic activation. No mutagenic effects could be observed in any of the five tester strains up to the highest dosage.

Packaging & Availability

Packaging Information

Pack size: 5 kg, 25 kg Sample size: 50 g

Storage & Handling

Shelf Life
1 year
Storage and Handling

At cellar to room temperature (15 – 25 °C), in well closed containers, protected from light.
Where possible, CutiBiome CLR should not be stored for longer than 1 year before processing.