Knowde Enhanced TDS
Identification & Functionality
- Carrier
- INCI Name
- Cosmetic Ingredients Functions
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Highlights
Recently, the term exposome has been defined as to all external exposure factors, with their interactions, that we face as humans during our life. It includes the body responses to those factors, most of them leading to clinical and biological signs of skin aging.
Among these factors are solar radiation (UV, visible and IR), environmental pollution, tobacco smoke, temperature, nutrition and others.
Solar radiation triggers the increase of ROS levels (reactive oxygen species), generating oxidative stress, which induces lipid peroxidation, mitochondrial and DNA damage and protein glycosylation (changes in the structure and function of proteins).
In addition, high levels of ROS also activate the extracellular matrix metalloproteinases (MEC), such as elastase, hyaluronidase and collagenase.
COBIOAGE brings a broad spectrum action, giving cosmetic formulas versatile efficacy, essential to meet the current demand presented by the skin aging exposome.
Applications & Uses
- Skin Care Applications
- Use Level
- 0.5% - 5%
- Cosmetic Use
- Protects from skin aging exposome
- Redensifying activity
- Anti-aging, anti-wrinkle and firming
- Protection of collagen, elastin and hyaluronic acid
- Anti-pollution
- Antioxidant
- Anti-glycosilation & Anti-lipid peroxidation
Properties
- Soluble in
- Water
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Properties
- Redensifying, anti-wrinkle, and firming: Due to its ability to inhibit hyaluronidase and collagenase, and its ability to induce collagen synthesis.
- Anti-aging, photoaging and anti pollution: protection: Thanks to its anti-oxidant capacity and protection against ROS damage, its protective effect against lipid peroxidation and protein glycosylation.
- Improves skin morphology, firmness and elasticity: Decreasing the SLEB band and improving the sub-epidermal density:
% Anti- Oxidant capacity
% Anti-Lipid peroxidation capacity
% Anti- Glycation capacity
SLEB Band Reduction 40-60 years old group D0-D56
Sub-epidermal density improvement 40-60 years old group D0-D56
The SLEB band presence is a marker of skin aging.
3% COBIOAGE reduced the SLEB band -24% improving the skin density +10,54 %.
Ultrasonography showing a decrease in the SLEB band, an improving in the sub-epidermal density and therefore in the skin morphology.