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COBIOCARE

COBIOCARE is a standardized extract from propolis obtained through a high efficiency patented process.

INCI Name: Propolis Extract

Functions: Anti-Microbial Agent, Anti-Pollution Agent, Anti-Septic, Deodorant

Ingredient Origin: Natural Origin, Non-Animal Origin, Plant Origin

Labeling Claims: Clean at Sephora, Credo Clean Standard, Natural, Naturally Derived, Organic, Plant-Based, Ulta Beauty's Conscious Beauty

Certifications & Compliance: COSMOS, ECOCERT, ECOCERT GREENLIFE, ISO 14001, ISO 22716, ISO 9001, Organic Certified

Benefit Claims: Anti-Bacterial, Anti-Inflammatory, Anti-Pollution, Antimicrobial, Antiseptic, Barrier Function Improvement, Good Oxidative Stability, Oxidation Protection, UV Protection

Technical Data Sheet
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Knowde Enhanced TDS

Identification & Functionality

Active Component
CAS No.
85665-41-4

Features & Benefits

Product Highlights

Propolis is a mixture of substances secreted by bees in order to protect them from exogenous factors like:

  • Bacteria and microorganisms
  • Oxidizing agents
  • Ultraviolet radiations

COBIOCARE contains a bio-active polyphenolic combination which reaches up to 15% in bioflavonoids and phenolic acids, with extraordinary antibacterial and antimicrobial properties.
The polyphenols portion is the responsible for the protection from exogenous agents. Our research has focused precisely on that part, investigating on possible similarities between the positive effects registered in the vegetable kingdom and the cosmetic efficacy: Biomimicry concept.
Among them there are Apigenin, Chrysin, Galangin, Pinocembrin, Pinobanksin, and Quercetin.

Applications & Uses

Bath & Shower Applications
Treatment Product Applications
Use Level
1.5% - 4%
Cosmetic Use
  • Safe, natural & efficient deodorants
  • Natural treatments for acne and acneic lesions
  • Antiseptic
  • Anti-inflammatory properties
  • Anti-pollution
  • Improves skin barrier function

Properties

Soluble in
Water, Ethanol

Regulatory & Compliance

Technical Details & Test Data

Properties

1) In-VIVO Test: Anti-pollution

4% COBIOCARE cream was tested on 20 volunteers in 3 different areas on forearm: 1 area is treated with the cream, 1 with placebo, 1 non-treated, exposed to 4-5 μm Carbon black powder to measure its antipollution efficacy:

 

% Black Spots Removed after wash

COBIOCARE - Properties

Based on its bactericidal activity, several In-vivo tests on its deodorizing activity and acneic lesion reduction were performed:

2) In-VIVO Test: Deodorizing Power

  • 20 subjects panel
  • Observations at 8h and 24h
  • Application of a deodorant containing 1,5% COBIOCARE
  • Clinical evaluation by experts on the base of a scale from 0 to 5, (corresponding to different odor perceptions).
  • Asymmetrical application (treated armpit/ non-treated)

COBIOCARE showed an odor reduction of 61%.

Objective Evaluation

 COBIOCARE - Properties - 1

 

3) In-VIVO Test: Reduction of acneic lesion

COBIOCARE showed a decrease of 60% in acneic lesions:

COBIOCARE - Properties - 2

 

  • 34 volunteers with Acne-Prone Skin.
  • Application of 4% COBIOCARE emulsion vs placebo
  • IGA-FDA 0-4 Acne Severity scale was used:0 = skin without lesions, 4= severe acne.

In-vivo test: Reduction of acneic lesion

COBIOCARE - Properties - 3