Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- INCI Name
- Cosmetic Ingredients Functions
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Highlights
Ingredients with antioxidant activity increase the whitening efficacy of cosmetic formulations. COBIOWHITE showed a potent antioxidant capacity reducing stress-induced reactive oxygen species (ROS) in keratinocytes.
As a complementary activity, COBIOWHITE prevents collagen and elastin degradation by inhibiting Matrix metallo-proteinases (MMPs) which is indicative of a potential firming, anti-aging and anti-wrinkle activity
Applications & Uses
- Application Format
- Skin Care Applications
- Use Level
- 0,5 - 2%
- Cosmetic Use
- Whitening treatments
- Photo-aging, brightening/lightening care
- Anti-age spot treatment
- Anti-oxidant
- Anti-aging and firming
Properties
- Soluble in
- Water
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Properties
The synergistic approach of COBIOWHITE makes it an ideal cosmetic active to reduce dark spots in aged skin:
1) -55 % Anti-tyrosinase and melanin activity
2) Anti-Oxidant Activity: Reducing ROS production in keratinocytes.
3) Anti-matrix metalloproteinase’s activity: Inhibits MMP9, MMP2 in fibroblasts, collagen and elastin degradative enzymes which contribute to the deterioration of the extracellular matrix resulting in wrinkles and skin age.
4) In-Vivo Whitening Activity: After a twice-daily treatment during 56 days with 1% COBIOWHITE, volunteers showed:- 21% Skin melanin reduction
- 25% Dark spot lightening
- Hyperpigmentation reduction in 80% of the volunteers
- Spot size and shape decreased in 75 % of the volunteers
Volunteer visioface images after 14, 28 and 56 days of twice-daily treatment with 1% COBIOWHITE shows the improvement and lightening of the cheek spot.