Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
- Source
HyWhite is produced by chemical modification of low molecular weight hyaluronic acid with α-linolenic acid. Hyaluronic acid is obtained by fermentation, α- linolenic acid is from a plant source.
Features & Benefits
- Benefit Claims
- Labeling Claims
- Production of HyWhite in Contipro
- Sustainable Biotech Production
- HyWhite is produced by chemical modification of very low molecular weight hyaluronic acid with α-linolenic acid. Our HA is made by fermentation of a non-haemolytic microbial strain Streptococcus equi.
- Enviromental Friendly Production
- Everything we make is biodegradable.
- We have our own solar power plant and wastewater treatment plant.
- Our buildings are heated with residual energy from our production operations.
- Sustainable Biotech Production
- Additional Advantages of HyWhite
- Effectively penetrates the skin
- Improves skin color uniformity
- Effective both in Asian and Caucasian type of skin
- Increases cell metabolism and energy production
- Stronger capacity to bind to the skin, it is not washed off easily as unmodified HA
Applications & Uses
- Markets
- Applications
- Compatibility and Processing
Sensitive to heat and high humidity; avoid prolonged heating (heating over 60 °C for 60 min can lead to a decreased degree of substitution and degradation by oxidation). Extreme pH (less than 4 or more than 10) leads to further decomposition. Incompatible with cationic substances, e.g. surfactants or polymers (polyquarternium-4, polyquarternium-10, etc.)
- Recommended Concentration in Final Product
0.005 - 0.01% of powder.
Properties
- Physical Form
- Soluble in
- Water, Aqueous mixture of ethyl alcohol and isopropyl alcohol
Regulatory & Compliance
- Certifications & Compliance
- Natural product
Contipro‘s HyWhite has natural origin index 1 (according to ISO 16128-1:2016 and 16128-2:2017)
Technical Details & Test Data
- Mechanism of Action
- Hyaluronic acid effectively delivers α-linolenic acid to the target – tyrosinase in melanocytes.
- α-linolenic acid increases degradation of tyrosinase – a key enzyme in melanogenesis.
- It is also a proteasome activator – the degradation of tyrosinase occurs via proteasome.
- In Vivo Study by Contipro
Lightening : 66% Lightening Effect
Whitening : 33% Decrease In Melanin Content
Spots Reduction : 20% Reduction Of Pigmented Spots
- Penetration - Franz diffusion cells, 24h at 37°
Storage & Handling
- Shelf Life
- 24 months