Knowde Enhanced TDS
Identification & Functionality
- Chemical Name
- Pharma & Nutraceuticals Functions
- Technologies
Features & Benefits
- Product Information
Exosomes are extracellular vesicles that are naturally secreted by many cell types and are heavily involved in cellular communication. Harvested exosomes contain valuable nucleic acids, proteins, and other molecules that have implications for wound healing, bone repair, and regeneration of numerous tissue types among many other applications. The nature of this 'cargo' is highly dependent on the type of cell the exosomes are derived from. They can also be loaded with specified molecules for a wide range of targeting capabilities.
This product consists of isolated and purified exosomes derived from human adipose MSC (mesenchymal stem cells). These stem cells are cultured ex- vivo in our laboratory. Stem cell exosomes provide the therapeutic benefits of live stem cells without the associated challenges and safety risks.
- Key Features
- Derived from adipose MSC
- Tested and Positive for: CD9, CD63, CD81
- Diluent: Dulbecco's Phosphate-Buffered Saline (No Cat+, No Mg++)
- Nanoparticles with typical diameter range of 50-150 nm
- Exosome concentration: 1 x 10^10 /ml verified by nanoparticle tracking analysis. See Figure I for representative analysis.
- Lot-specific analysis available by request.
Figure 1. Size and concentration distribution shown by nanoparticle tracking analysis.
Applications & Uses
- Markets
- Applications
- Preparation
- Thaw on ice
- Dilute to desired concentration and aliquot
- Recommended to store in working aliquots at -80 °C
- Avoid exposing to more than 4 freeze-thaw cycles
Safety & Health
- Precautions
This product is intended for R&D use only. Not for human consumption, household, or other uses.
Storage & Handling
- Storage Conditions
- Shipped on dry ice.
- Store at -80°C.
- Stable for up to 1 year at -80°C as supplied.
- Can be stored for up to 48 hours at 2-8 °C.