Knowde Enhanced TDS
Identification & Functionality
- Active Component
- Ingredient Name
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
Features & Benefits
- Benefit Claims (Health)
- Food Ingredients Features
- Beneficial Properties of Fermentation Process
- Oxygen control
- Correct species and strains
- Fullycontrolled continuous fermentation
- Temperature control
- Qualitative & quantitative active substances
- Low risk of contamination
- Optimum pH value control
- Closed pure culture
- Optimal nutrients
- Health Benefits
- Unique adaptogen that counteracts the negative effects of stress
- One of the most superior antioxidants in the plant world
- Helping slow down aging by means of AMPK activation
- Lowering blood glucose and Hemoglobin A1c (HbA1c) levels by significantly improving the insulin sensitivity of the cells
- Supporting cardiovascular health by neutralizing the oxidative damage to the arteries and regulating the blood pressure by stimulation of nitric oxide (NO)
- Modulating the immune system
- Promoting weight loss by activating AMPK and improving insulin sensivity
- Having anti-viral, anti-fungal and anti-bacterial properties and can be used in the prevention of colds and the flu
- Why Ferment Jiaogulan?
An innovative functional-oriented and microbial fermentation creates a biotransformation of the secondary metabolites of jiaogulan. During fermentation microbial enzymes transform poorly available herbal components into more easily absorbable health-promoting metabolites!
What is this transformation all about?
The active components of the jiaogulan plant are essentially gypenosides, also called saponins. The fermentation of plant extracts is still very new, and the focus is mainly on the conversion of the original glycolised saponines to the more active form. Due to their bulky molecular structures, the gypenosides are poorly membrane permeable and must therefore be further degraded. The mass of the original gypenosides decreases after fermentation due to the removal of the sugar molecules from the gypenosides. This process is called deglycosylation. The form is the so called aglycone form, which is permeable and hence directly bioactive. Smaller molecules that are very active and well-studied, penetrate the body more easily!Formation of new components as the rare ginsenosides
Enrichment in Compound K, Rg3 and Rh2 : HPLC fingerprint analysis of rare ginsenosides in wildgrowing jioagulan before (A) and after (B) fermentation. In comparison with native (unfermented) wild-growing jiaogulan, fermented wild-growing jiaogulan contains about:- 13-fold more ginsenoside CK (Compound K)
- anti-inflammatory effect
- 3-fold more ginsenoside Rg3
- tumor inhibition
- 2-fold more ginsenoside Rh2
- neuroprotective
(A) HPLC profile of native (unfermented) wild-growing jiaogulan
(B) HPLC profile of fermented wild-growing jiaogulan
AMPK activation by: Gypenosides Compound K, Rh2
- 13-fold more ginsenoside CK (Compound K)
- Product Highlights
- Conversion of the saponins (gypenosides) to their bioactive form
- Higher bioavailability of all active substances
- Formation of SOD-like substances or smaller active antioxidant molecules
- Much lower daily dose needed
Applications & Uses
- Markets
- Food & Nutrition Applications
- Use Level
- 300 - 500
- Uses
- Nutritional supplements
- Functional food
Properties
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Total Gypenosides | min. 110 | mg/g | — |
Technical Details & Test Data
- Science
Many studies show the therapeutic properties of jiaogulan. It is therefore scientifically very well founded. However, it is important that the gypenosides are available in their easily absorbable form because this is a condition for the therapeutic power of this promising plant.