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Fine Chemicals Guanidine Thiocyanate

Guanidine Thiocyanate is a white crystal with chemical formula C₂H₆N₄S.

Chemical Name: Guanidine Thiocyanate

CAS Number: 593-84-0

Chemical Family: Thiocyanates

Functions: Chaotropic Agent, Denaturant, Intermediate

Synonyms: GTC, Guanidine isothiocyanate, Guanidinium isothiocyanate, Guanidinium thiocyanate, NSC 2119

Technical Data Sheet
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Identification & Functionality

Chemical Family
CAS No.
593-84-0
EC No.
209-812-1
Chemical Structure

Fine Chemicals Guanidine Thiocyanate - Chemical Structure

Specialty Chemicals
As a chaotropic agent, isolating DNA/RNA, denaturing proteins

Applications & Uses

Markets
Applicable Processes
Applications
Guanidine Thiocyanate is a strong protein denaturant used in RNA isolation. It is also used as a storage buffer for blood samples. Guanidine thiocyanate inactivates nucleases and is ideal for storing and freezing samples for DNA studies. It is used in combination with phenol−chloroform in RNA extraction.

Properties

Physical Form
Appearance
White powder, White crystals
Typical Properties
ValueUnitsTest Method / Conditions
Assay Contentmin. 99%
Loss on Dryingmax. 0.50%
Melting Point118-121⁰C
Copper Contentmax. 1ppm
Lead Contentmax. 1ppm
Zinc Contentmax. 1ppm
Particle Size Distribution
ValueUnitsTest Method / Conditions
Particle Size100-400microns

Technical Details & Test Data

Notes
Product does not contain any DNases, Rnases, Proteases or Phosphatases.

Safety & Health

Caution
Material may irritate eyes. May be harmful if swallowed. Avoid contact with eyes, skin, and clothing. Keep in tightly closed container. Wash thoroughly with water after handling. Store separately from heat, flame and strong oxidizers. Store in original packaging.