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SIGDerma Clean & Sensitive

Innovative state of research Isoprenylcysteine (IPC) specifically against acne without harmful side effects. Effective against acne and inflammations (IL-8, IL-17), anti-bacterial. Suitable for: Anti-Acne & Dermatological Care.

INCI Name: Disodium Tetramethylhexadecenylcysteine Formylprolinate

Functions: Anti-Acne Agent, Anti-Aging Agent, Anti-Microbial Agent

Benefit Claims: Anti-Acne, Anti-Bacterial, Anti-Inflammatory, Free Radical Scavenging, Irritation Reduction, Skin Protection

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Knowde Enhanced TDS

Identification & Functionality

CAS No.
2040469-40-5, 2422121-34-2

Features & Benefits

Cosmetic Benefits
  • SIG 1459 is a proprietary Isoprenylcysteine (IPC) molecule developed by Dr. Jeffry Stock
  • clinically proven to outerform benzoyl peroxide (BPO) statistical significance ober 8 weeks in thosed with acne prone skin
  • not irritating the skin unlike BPO
  • anti-bacterial activity, kills acne and works effectively better than BPO or salicylic acid
  • in epidermal keratinocytes SIG 1459 strongly inhibits TLR2/2 and TLR2/6 induced IL-8 release
  • blocks T-cell receptor induced IL-17 production, which has been reported to contribute to acne pathogenesis

Applications & Uses

Application Format
Treatment Product Applications
Use Level
0.1 - 1 %

Properties

Physical Form
Appearance
Off-White to Light Brown Solid
Insoluble in
Alcohols or Oils
Soluble in
Miscible Water (min. 10 %)