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INCI Name: Hydrolyzed Wheat Protein, Sodium Benzoate

Functions: Hair Growth Inhibitor

Labeling Claims: BSE-free, CMR Substances-free, Clean at Sephora, Credo Clean Standard, GMO-free, Gluten-free, Halal, Impurities-free, Nanomaterials-free, Natural, Not Tested on Animals, Solvent-free, Sustainable, TSE-free, Ulta Beauty's Conscious Beauty, VOC-free, Vegan

Certifications & Compliance: EU Cosmetic Regulation 1223/2009 Compliant, FDA Compliant, GMP, Halal, ISO 16128, ISO 22716

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Knowde Enhanced TDS

Identification & Functionality

Carrier
Cosmetic Ingredients Functions
EINECS No.
231-791-2, 208-534-8, 305-225-0
Origin
  • Aqua - Mineral
  • Hydrolyzed Wheat Protein - Vegetable
  • Sodium Benzoate- Synthetic

Features & Benefits

Action
  • Limits hair regrowth
  • Reduces pilosity
Cosmetic Benefits

Hair regrowth is slowed and the time between 2 depilations is extended; skin remains smoother and softer.

Applications & Uses

Application Format
Hair Care Applications
Skin Care Applications
Cosmetic Application
  • Depilation products
  • Anti-regrowth products
  • After-shave care products
  • Deodorants/Antiperspirants
Formulations

Concentration for use: 2 to 5%

Caution for use: Add to emulsions, at the end of the preparation process, either cold or at
35-40°C, during cooling.

Properties

Physical Form
Odor
Characteristic
Appearance
Liquid
Soluble in
Water, 10% in water
Typical Properties
ValueUnitsTest Method / Conditions
Natural Content0%-
Natural Origin Content98.9%-
Quantifications
ValueUnitsTest Method / Conditions
Ashesmax. 1.5%Ph. Eur.
Total nitrogen compounds (Kjeldahl)2.0 - 3.5%NF EN 25663
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
Dry Matter21.0 - 24.0%GT006
pH Value (Direct)4.0 - 5.0-GT005
Microbiological Values
ValueUnitsTest Method / Conditions
Detection of EnterobacteriaAbsence-ISO 18415
Enumeration of Mesophilic Aerobic Bacteriamax. 100ufc/mL - cfu/mLISO 21149
Enumeration of Yeasts and Moldsmax. 100ufc/mL - cfu/mLISO 16212

Regulatory & Compliance

Chemical Inventories
REACH Status
INCI Concentration REACH Status
Aqua 77.9 % Water exempted annex IV
Hydrolyzed Wheat Protein 21 % Exempt: < 1 ton/year (dry matter)
Sodium Benzoate 1.1 % Sodium Benzoate
registered n°01-2119460683-35

 

Technical Details & Test Data

Mechanism of Action

Dual action:
Rosebay willowherb contains high concentrations of proline that inhibits the formation of the keratin helix. Saw palmetto and pumpkin inhibit 5-α-réductase, limiting the production of 5-hydroxy-testosterone, which in turn limits hair bulb activity.

Scientific Process
  • Pilosity

The factors affecting hair structure are mainly hormonal: the presence of dihydroxytestosterone (active form of testosterone) in the hair bulb is due to the activity of the enzyme 5-α-reductase (it converts testosterone into dihydroxytestosterone). Any substance capable of inhibiting this enzyme will delay hair growth.

  • ARP 100

Proline, an essential amino acid contained in rosebay willowherb, limits hair regrowth by inhibiting the formation of the keratin helix. Rosebay willowherb also contains macrocyclic tannins that limit testosterone production. Saw palmetto extract inhibits 5-α-reductase. This action is further reinforced by the anti-androgen effect of pumpkin.
Thanks to its hormone-like effect, ARP 100 contributes to inhibiting hair regrowth.

Proven Efficacy - In Vivo Test

VIDEOMICROSCOPIC STUDY (10 VOLUNTEERS)

  • Hair regrowth is reduced by 34%, after two depilation cycles (daily application of a 5% lotion for 5 days after depilation)

Glialys - Proven Efficacy - in Vivo Test

 

  • Pilosity is reduced by 21%

Glialys - Proven Efficacy - in Vivo Test - 1 

Storage & Handling

Shelf Life
24 months
Storage

15 / +25°C
Keep in the original packaging, without opening, in the recommended storage conditions.
Advice before use : Agitation