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GREENTECH Research thus developed LACTOPHYT®, based on the potential of Lactococcus lactis, a lactic bacteria producing a specific antibacterial activity. A new production process maximizes this antibacterial activity and gives an extract obtained by fermentation rich in bacteriocins and organic acids. To reinforce the selectivity of this ingredient, GREENTECH has demonstrated a synergy between this extract from bacterial origin and a low concentration of Glyceryl caprylate, an emollient also possessing an antibacterial activity.

INCI Name: Decyl Glucoside, Glyceryl Caprylate, Lactococcus Ferment Extract

Functions: Deodorant

Labeling Claims: BSE-free, CMR Substances-free, Clean at Sephora, EDTA-free, GMO-free, Gluten-free, Glycol ether-free, Impurities-free, Nanomaterials-free, Natural, Nitrosamines-free, Not Tested on Animals, Organic, Phthalates-free, Preservative-free, Solvent-free, Sustainable, TSE-free, VOC-free, Vegan

Certifications & Compliance: CFDA Compliant (China), ECOCERT, EU Cosmetic Regulation 1223/2009 Compliant, FDA Compliant, GMP, IECIC (China), ISO 16128, ISO 22716, Organic Certified

Benefit Claims: Comforting, De-Odorizing, Long Lasting Freshness, Mycobiota Restoration

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Knowde Enhanced TDS

Identification & Functionality

Cosmetic Ingredients Functions
EINECS No.
231-791-2, 207-997-3, 247-668-1
Origin
  • Aqua - Mineral
  • Propanediol - Vegetable
  • Glyceryl Caprylate - Vegetable
  • Lactococcus Ferment Extract - Bacterial
  • Decyl Glucoside - Vegetable

Features & Benefits

Product Highlights

Our skin is an interface with the outside environment and, as such, is colonized by a diverse microbiota community. Certain bacterial species present in the axillary community have the capacity to transform non-odorous substances into volatile odorous substances by the action of enzymes. We can mention a very special involvement of Corynebacterium spp. and Staphylococcus spp.
The repeated use of deodorant to destroy the bacterial flora of the axillary microbiota does not appear to be the appropriate solution: bacterial abundance is decreased and led to the proliferation of inapropriate bacterial community when classical deodorant are stopped.
For this reason, GREENTECH designed a new active which limits proliferation of bad odors responsible bacteria without suppressing the other strains.

Action
  • Reduces bacteria responsible for bad odors
  • Maintains “good” bacteria
  • Limits armpit bad odors
Cosmetic Benefits

While preserving beneficial bacteria to respect microbiota balance, axillary bad odors disappear. LACTOPHYT® brings a sensation of comfort and freshness.

Applications & Uses

Application Format
Personal Hygiene Applications
Cosmetic Use
  • Deodorant
  • Hygiene products
Formulations
  • Concentration for use: 2 %
  • pH for use: 4.0 - 6.0
  • Caution for use: Add to emulsions, at the end of the preparation process, either cold or at 35-40°C, during cooling.

Properties

Physical Form
Odor
Characteristic
Appearance
Liquid
Soluble in
Water, Propanediol
Partially Soluble in
10% in ethanol, 10% in water
Quantifications
ValueUnitsTest Method / Conditions
MIC against Brevibacterium epidermidismax. 1%GT121
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
Refraction Index1.370 - 1.410-GT007
Specific Gravity1.000 - 1.060-GT008
pH Value (Direct)4.5 - 5.5-GT005
Microbiological Values
ValueUnitsTest Method / Conditions
Detection of EnterobacteriaAbsence-ISO 18415
Enumeration of Mesophilic Aerobic Bacteriamax. 100ufc/mL - cfu/mLISO 21149
Enumeration of Yeasts and Moldsmax. 100ufc/mL - cfu/mLISO 16212

Regulatory & Compliance

REACH Status

 

INCI Concentration REACH Status
Aqua 43 - 52.9 % Water exempted annex IV
Propanediol 42 - 46 % Propanediol registered
n°01-2119489383-28
Glyceryl Caprylate 3 - 8 % Glyceryl caprilate
registered n°01-2120119773-55
Lactococcus Ferment Extract 2 - 4.5 % Exempt: < 1 ton/year (dry matter)
Decyl Glucoside 0.1 - 1 % Decyl glucoside
registered n°01-2119488530-36

 

Technical Details & Test Data

Scientific Mechanism

The objective is to limit the proliferation of species involved in the formation of malodour compounds.

Lactophyt® - Scientific Mechanism

Axillary microbiota                        Decrease of bacterial species responsible of bad odors

                                                          

Proven Efficacy

LACTOPHYT® limits growth of strains involved in the production of unpleasant odors, without disturbing “beneficial” bacteria competing with bacterial species generating bad odors.

Correlation between
bacteria and bad odors
LACTOPHYT® at 2% (v/v)
No directly involved SPECIES 24h 48h 72h

Positively correlated
with olfactory descriptor
(global, spivy or fresh onion)

S. EPIDERMIDIS + + +
S. HOMINIS - - +
C. XEROSIS - - -
C. TUBERCULOSTEARICUM - - -

Initial bacterial concentration of 105 CFU/mL
Incubation at 37°C
The growth is considered as positive (+) when the OD600 is greater than 0.1 (compared to initial OD600 at 0h)
S. epidermidis: Staphylococcus epidermidis; S. hominis: Staphylococcus hominis; C. xerosis: Corynebacterium xerosis; C. tuberculostearicum: Corynebacterium tuberculostearicum

 

Staphylococcus epidermidis

Lactophyt® - Proven Efficacy

 

Staphylococcus hominis

Lactophyt® - Proven Efficacy - 1

 

Corynebacterium xerosis

Lactophyt® - Proven Efficacy - 2

Initial bacterial concentration of 105 CFU/mL in presence of LACTOPHYT® (2%)
Results obtained after 8,24 and 32 hours of incubation at 37°C

 

LACTOPHYT® selectively reduces the bacteria responsible for bad odors, preserving the axillary microbiota.

Clinical Study

COMPARISON WITH PLACEBO

Double blind test with 18 volunteers. One daily application on armpit during 3 days with
LACTOPHYT® 2% versus an active formula containing talc and a perfume (here named
placebo). Auto-evaluated sniff-test on a 0 to 6-scale from no odor to very strong odor
(disturbing others).

DAY 1
ODOR INTENSITY

Lactophyt® - Clinical Study

 

DAY 3
ODOR INTENSITY

Lactophyt® - Clinical Study - 1

* p<0.05 / vs placebo

LACTOPHYT® has a higher deodorant power than placebo.

 

COMPARISON WITH TRIETHYLCITRATE

Double blind test with 20 volunteers. One daily application on armpit during 3 days with
LACTOPHYT® 2% versus TRIETHYLCITRATE 1% (percentage usually used). Auto-evaluated sniff test on a 0 to 6-scale from no odor to very strong odor (disturbing others).

 

DAY 1
ODOR INTENSITY

Lactophyt® - Clinical Study - 2

 

DAY 3
ODOR INTENSITY

Lactophyt® - Clinical Study - 3

* p<0.05 / vs Triethylcitrate

LACTOPHYT® has the same deodorant power as Triethylcitrate currently use on the market.

Lactophyt® has a high deodorant power based on its capacity to inhibit growth of bacteria involved in the production of unpleasant odors.

Safety & Health

Toxicological Tests
Tests Method Tested Concentration Results
Eye Irritation Het cam 2 % Slightly irritant
Sensitization HRIPT 2 % Very good skin compatibilit
Skin Irritation Patch Test 2 % Very good skin compatibility

 

Storage & Handling

Shelf Life
12 months
Storage

15 / +25°C
Keep in the original packaging, without opening, in the recommended storage conditions.
Advice before use : Agitation