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Herb Nutritionals Conjugated Linoleic Acid refers to a group of chemicals found in the fatty acid linoleic acid. According to the review of the Wikipedia, at least 28 isomers of linoleic acid are found in the conjugated linoleic acid (CLA). CLAs can be either cis- or trans-fats and the double bonds of CLAs are conjugated and separated by a single bond between them.The United States Food and Drug Administration (FDA) categorizes Conjugated linoleic acid （CLA） as generally recognized as safe (GRAS) status for certain food categories, including fluid milk, yogurt, meal replacement shakes, nutritional bars, fruit juices and soy milk. With GRAS status, dietary supplement companies are able to add CLA to products in these food categories.

Herb Nutritionals (R)-alpha-Lipoic Acid(R-ALA) is the biologically active component (native to the body) that is responsible for lipoic acid’s phenomenal antioxidant effect. The “S” form is produced from chemical manufacture and is not very biologically active. Typical alpha-lipoic acid supplements consist of the “R” and “S” form in a 50/50 ratio. That means a 100 mg alpha-lipoic acid supplement is providing 50 mg of the biologically active “R” form.