Browse Products by Market

Browse Products by Technology

Incospharm was founded in 2011 and is continually developing peptides for anti-wrinkle, moisturizing, anti-oxidant, and brightening of the skin. AQUATIDE has significant activity of cellular autophagy induction, enabling and maintaining healthier skin. Active ingredients for sensitive and troubled skin where aging process is faster than normal skin are also under development for cosmetics or pharmaceutical applications. Incospharm has partnered with Arysta Health and Nutrition Sciences (Tokyo, Japan) for global sales and marketing since its foundation.

Privacy

Terms & Conditions

Terms of Sale

Cookie Policy

Natural moisturizing factor (NMF) in the stratum corneum has a high moisture retaining efficacy, and plays a major role in the skin barrier function.
Pyrrolidone carboxylic acid (PCA) is one of the major NMFs found in human skin.
Aquatide, PCA-mimetic peptide, increases moisturisation, activates autophagy, reduces Trans Epidermal Water Loss (TEWL) and improves the skin barrier function.

Aquatide

AdipoSOL

AdipoSOL™ 2000 is a novel anti-photoageing ingredient that protects the skin from UV stress through autophagy induction and adiponectin expression in skin cells. Shifting of MED proves its skin protection against UV. UV exposure decreases the expression of adiponectin, a well-known adipokine, secreted by adipocytes, leading to the exacerbation of photoageing by stimulating MMP-1 expression and inhibiting procollagen synthesis. Thus the repeated skin damage and imperfect repair caused by UV exposure results in “photoageing” and “inflammageing”.

AdipoSOL™ 2000

Incospharm Corporation Pineapple Ceramide is the major intercellular lipid filling the gaps in corneocytes of horny layer, the outer layer of skin, and plays an important role in suppression of transepidermal water loss, skin barrier function to interrupt invasion of foreign substances or maintenance of skin structure. It is known that ceramide decreases with aging or atopic dermatitis.

Incospharm Corporation Pineapple ceramide

Incospharm Corporation PolluxCD is a novel natural extract that protects the skin against various air-pollution stress (PM, BaP, Heavy metals, UVB) and prevents pollution-induced skin aging.

Incospharm Corporation PolluxCD

Incospharm Corporation Glyceryl Glucoside is a conjugated molecule of glycerol and glucose, and was originally found to be critical for cyanobacteria survive in extremem conditions. Recently, many scientific reports suggested the key role of glyceryl glucoside in induction of aquaporin-3 protein, which is an essential protein in water molecule transport across the skin cell membrane. Glycerol glucoside is becoming the new molecule for next generation moisturizing ingredient.

Incospharm Corporation Glyceryl glucoside

Incospharm Corporation MelaTrepein are transferred to neighboring keratinocytes and then naturally degraded by autophagy. However, when the skin is constantly exposured to sunlight, pathogens, and hormone changes, the intracellular organelles and enzymes lose their functions and, as a result, melanosomes can not be degraded down. Accumulation of undegraded melanosomes in keratinocytes results in skin pigmentation.

Incospharm Corporation MelaTrepein

Aquatide 5000 is the first known peptide-derived SIRT1 activator, activates SIRT1 by direct interaction. Through this interaction AQUATIDE 5000 increases a deacetylation of SIRT1 target protein FoxO1, resulting in the cell protective autophagy.

Aquatide 5000

Incospharm Corporation Wasabi Flavone is the typical herbal medicinal spice originated in Japan known for its anti-bacterial and anti-toxin activities. These activities are due to a special flanovoid called isosaponarin identified from the wasabi flavones extract. Wasabi flavones not only facilitates intracellular collagen biosynthesis, but also helps collagens to form triple helix structure, which is essential for wrinkle reduction and enhanced elasticity of the skin.

Incospharm Corporation Wasabi Flavone

Incospharm Corporation rhEGF is a member of the EGF-like family of proteins. It stimulates the growth and differentiation of fibroblasts and epithelial cells, and plays a role in the development and regeneration of various tissues. EGF is synthesized as a precursor protein that remains anchored to the cell surface. Release of the soluble form occurs through a process known as ectodomain shedding, which involves cleavage of the extracellular domain by the proteins disintegrin and ADAM17. EGF signals via EGF receptor (EGFR, ErbB1 or HER1), which is a type 1 tyrosine kinase receptor and can also bind several other EGF-like proteins. Binding of EGF to EGFRs trigger receptor dimerization, autophosphorylation and internalization of the receptor-ligand complex. Recombinant human Epidermal Growth Factor, from E.coli, is a 6.2 kDa protein containing 53 amino-acid residues.

Incospharm Corporation rhEGF

Incospharm Corporation Sebodulin restores healthy hydrolipidic film by activation of autophagy in sebocytes, the sebum making cells in skin. Sebodulin also help to alleviate the inflammatory responses by C. acne and to improve the skin barrier function

Incospharm Corporation Sebodulin

Incospharm Corporation

Incospharm was founded in 2011 and is continually developing peptides for anti-wrinkle, moisturizing, anti-oxidant, and brightening of the skin. AQUATIDE has significant activity of cellular autophagy

Incospharm Corporation - Knowde

Website

Personal Care

Markets

With TDS

Knowde is the first marketplace for chemicals, polymers and ingredients. Our leading-edge digital capabilities connect thousands of sellers and buyers every day.

Products - Incospharm Corporation - Knowde

Skin Barrier Protectant

Physical Form

Job Title

Shipping Terms

Name

and the data associated with it — permanently.

This is a Premium Feature

Changes to filters have not been applied.

Discard changes?

{userCompanyName} notice

In order to join {userCompanyName} on Knowde, you must use your business email address.

Business already on Knowde

{userCompanyName} requires all users on {companyName} to register with their business email address to ensure confidentiality and security.

{userCompanyName} requires registering your business email address

There's only a little ways to go.

Creating an account is free and the only way to directly download documents, order samples, request quotes and use direct messaging.

Quit Sign Up?

Tell us about {userCompanyName}

from concierge@knowde.com

Click the link in the email, or enter the 6-digit code

Verification email sent

Since you’re using a personal email address, we require proof to verify the information you have provided.

Please verify your account

Please go back and enter in an email address that is directly associated with a business.

Knowde is built for businesses

Also, using a personal email for creating your {companyName} account may require additional verification of your company details.

We recommend signing up with a work email address to get faster responses, especially when requesting samples, documents, and more.

Please enter your business email address below.  We’ll send you a confirmation code to quickly verify.

Enter your business email

{companyName} uses Knowde for account management so you can manage all of your sample requests, RFQs, orders and more in one place.

Knowde is for businesses, you may have a hard time receiving responses to your requests if you use a personal email address.

to {email}

We sent an email to {email}

Please click the link to reset your password

Check your email

Create a new password

Password expired

Sign in to {companyName}

Enter a new secure password

Change your password

Enter the email address associated with your account

Reset your password

Enter your password for

Use your Knowde password to sign in:

Please provide additional information to help us verify your company.

Terms and Conditions

Compare multiple products at once and find the best fit for your project needs.

Why is this important?

Enter your password

Unlock your account

Knowde is the world’s biggest marketplace to search for ingredients, polymers, and chemistry. You can:

Welcome to Knowde

View All Products

Cart

Please fix the following before proceeding to payment

An order receipt has been emailed to {email}

Order

This feature is currently unavailable at this screen size.

Payment

Shipping

Checkout

KEEP IN MIND

You will lose any existing chat history by starting a new chat.

Start a new chat?

Compare Products

{price} each for {name}

This document is restricted content.

If you believe you should have permission to this document, please request access.

Restricted Access

It only takes 60 seconds to create an account.

Available {documentType} documents for this product ({counter})

Describe Documents You’d Like to Request

Invalid job title

That’s not the reaction we were expecting.

Page not found - Store for chemicals, polymers and ingredients

Internal Server Error - Store for chemicals, polymers and ingredients

Unexpected error occurred. Please contact us.

Client Side Exception - Store for chemicals, polymers and ingredients

Show products with

Filters

Featured Products

Flavor & Taste Explorer

Flavor Families

Enter your inquiry here, include as much detail as you’re able. *

To submit an inquiry to {companyName}, please fill out the form below and click Submit. They will get back to you as soon as they’re able.

Home Page

Request samples, documents, and quotes directly from suppliers

{companyName} experts - Knowde

Knowde is the first marketplace for chemicals, polymers and ingredients. Our leading-edge digital capabilities connect thousands of suppliers and customers every day.

Chemicals Marketplace - ingredients & raw materials - Knowde

Learn how to take full advantage of the free to use tools that you have unlocked.

Explore the capabilities of the platform and get immediate assistance for your needs with one of our experts.

Schedule a Demo

You’ll meet with Kiana from our Knowde Marketplace Team

Explore the capabilities of the platform and get immediate assistance for your needs.

Learn how you can make the most of the free tools now available to you.

Explore the capabilities of the platform with our dedicated team.

Weekly Webinar

See which others might better fit your needs.

This is just one of {allProducts} products on Knowde.

BROWSE THE MARKETPLACE BY

Knowde for Suppliers

Most popular categories

Gain instant access to our marketplace of over 250,000 chemicals, ingredients and polymers from 8,000 suppliers. Browse, search, and filter to quickly compare products, find information, request documents, order samples, and get quotes directly from suppliers.

Search and filter over 250,000 chemicals, ingredients and polymers, access documents and download starter formulations. Interact with over 8,000 suppliers whose representatives are ready to help. Sign up for a free Knowde Marketplace account today.

Create a free account to gain instant access to our marketplace of over 250,000 products and their documents.

Get new products to market faster with a free Knowde Marketplace account

The fastest way to find the right raw materials for your products

Want to explore more products?

Popular {companyName} Products

Start Order

Get a Quote

1 of {brandProductsCount} products in this brand

This will be used for any follow-up questions so we can best meet your needs

Please fill out the form below to help {companyName} prepare your quote

Your request has been sent to {companyName}

This information will help us get you the right materials.

All Categories

{numberOfResults, plural, one {Brand} other {Brands}}

{numberOfResults, plural, one {Product} other {Products}}

Search Tips

{charactersCounter}/{limitCharacters} Characters

Visit

Your account has been verified. You now have access to the full power of {companyName}

The quantity your business will require annually, if the sample product suits your project's needs.