Knowde Enhanced TDS
Identification & Functionality
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
- Key Features
Cosmetic active ingredient able to offer a “photo-aging” protection, repairing the skin from damage caused by chronic exposure to sunlight, including UV, Blue light and IR. SPF booster activity.
- In vitro and Clinical Actions
- Rescue of UV-damaged skin fibroblasts and stimulation of Cell viability
- Inhibition of pro-inflammatory mediators and Extra Cellular Matrix (ECM) degradation enzymes (Proteomic analyzes)
- Increase in collagen and components for Extra-Cellular Matrix (ECM) cohesion (Proteomic analyzes)
- Protection against blue light (ROS assay)
- Soothing properties on skin redness induced by UV radiations (Mexameter®)
- SPF booster (Spectrophotometer)
- Maintenance of mitochondrial activity
- Inhibition of MMPs
- Efficacy supported by proteomics
Applications & Uses
- Markets
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.2 - 2%
- Applications
- Anti-aging, anti-wrinkle
- Protection/repair of environmental damage
- Day creams with or without UV filters
- Sun care
- Sunscreens
- Anti-aging formulations
- Post-UV repair cream
- Formulation Procedures
Incorporate in a formulation at a maximum of 40°C, during cooling phase or at the end of the preparation.
Properties
- Physical Form
- Soluble in
- Water, Glycerin, Propylene Glycol
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Test Data
Rescue of UV-damaged skin fibroblasts with Plant C-Stem™ Vigna radiata
- The addition of Plant C-StemTM Vigna radiata increased cell viability by 2.3-fold
- The Plant C-StemTM Vigna radiata stem cell vacuole extract rescued the viability of human skin fibroblasts previously exposed to UVB
Inhibition of IL-8 Secretion anti-inflammatory action
- Plant C-Stem™ Vigna radiata significantly reduces IL-8 secretion.
Reduction of UV-Induced Erythema
- Plant C-Stem™ Vigna radiata reduces UV-induced erythema after one single application.
Blue Light protection
ROS assay - blue light-induced oxidative damage
Blue light exposure causes the production of Reactive Oxygen Species (ROS)
- Plant C-Stem™ Vigna radiata significantly reduces the ROS production in cells stimulated with blue light (≈ 400 nm), showing a protective activity against blue light
Infrared protection
ROS assay – infrared-induced oxidative damage
Infrared exposure causes the production of Reactive Oxygen Species (ROS)
- Plant C-StemTM Vigna radiata significantly reduces the ROS production in cells stimulated with infrared (≈ 800 nm), showing a protective activity against infrared
Storage & Handling
- Shelf Life
- 3 Years
- Storage and Shelf Life Conditions
- In original sealed containers, in a cool and dry place, protected from light.
- Cloudiness or sedimentation is normal and may be resolved by rotating the unopened drum.
- 3 years, stored unopened in original containers.
- Once opened the shelf life is limited by temperature, light and exposure to air.