KALIBIOME ORIS

Identification & Functionality

Ingredient Origin

Fermentation

Cosmetic Ingredients Functions

Oral Care Agent

Technologies

Cosmetic Ingredients

Product Families

Cosmetic Ingredients — Cosmetic Actives

Oral Care Agents

Features & Benefits

Benefit Claims

Anti-Inflammatory,

Barrier Function Improvement,

Healing,

High Purity,

Irritation Reduction,

Regenerating,

Repairing,

Skin Microbiome,

Soothing,

Stimulates Immune System,

Strengthening

Labeling Claims

Palm Oil-free,

Preservative-free

Product Information

It Promotes:

• Oral fibroblast and keratinocytes damage repair
• Reduction of gingival inflammations
• Modulation of the oral immune system
• Microbiota balance improving & soothing action, homeostasis keeping
• Halitosis prevention

Categories:

• Functional Actives
• Oral Hygiene

Kalibome Postbiotics: New Concepts

• Concentrated and reproducible postbiotics complex
• Obtained by controlled bio fermentation , finalized to select a specific actives output
• No bacterial fragments toxins , only ferment actives
• Total absence of side effects and maximum tolerability
• No culture broth or living bacteria , preservatives free
• No interference with cosmetics preservatives
• Powder form
• Low concentration of use required (0.1 ÷ 0.5 %)
POST biotics
Concentrated biotech active specialties . Fermentation carried in minimal media & controlled conditions. No living bacteria, residual food or bacterial fragments. Direct beneficial effects on skin and microbiota. Highly reproducible composition. White, soluble, colorless, odorless powder with concentrated actives.
* Patented fermentation process
STRAIN S ELECTION FOR POSTBIOTICS PRODUCTION
Postbiotics were obtained from Lactobacillus Paracasei a commensal microorganism that showed beneficial effects on host including a significant anti caries activity

Kalibome Targets VS Periodonits

1) Immune system rebalancing through cytokines/chemokines release modulation, aimed to the inflammation control
2) ROS inactivation to keep under control the periodontal tissue damage related to oxidative stress
3) Microbiota unbalance control and biofilm formation prevention
4) Oral mucosa barrier function restoring

Key Attributes

Immunomodulation	Tissue Regeneration	Epithelial Barrier Strengthening	Microbial Control
Gingival tissue inflammation	Oral mucosa repair	Oral mucosa defenses	Dental plaque
Gums irritation , redness & recession	Wound healing	Gums & teeth sensitivity	Oral microbiota balance
			Cavities & tartar
			Halitosis

 

Applications & Uses

Application Format

Gel,

Rinse Off,

Spray

Oral Care Applications

Mouthwash,

Toothpaste

Application Fields

• Microbiota Care
• Oral Hygiene

Applications

• Overnight treatments
• Gingival gels
• Mouthwashes
• Toothpastes
• Mouth sprays

Properties

Physical Form

Powder,

Solid

Microbiological Values

	Value	Units	Test Method / Conditions
Total Microbe Count	0 - 100	UFC/g	Internal

Regulatory & Compliance

Certifications & Compliance

ISO 16128