Knowde Enhanced TDS
Identification & Functionality
- Active Component
Features & Benefits
- Labeling Claims
- Food Ingredients Features
- A Nutritional View
High blood cholesterol level is the first risk factor for coronary heart disease. Studies have shown that a 10% decrease in blood cholesterol level can reduce the risk of cardiovascular disease by 19% to 54% depending on a person's age.
The cholesterol lowering effect of plant sterols is well documented in the literature. Consumption of 1.5 to 2.4 grams of plant sterols per day can lower LDL-Cholesterol by 7% to 10%. The European Food Safety Authority (EFSA), has approved claims for plant sterols namely: i)"plant sterols have been shown to lower/ reduce blood cholesterol 2" and ii)"plant sterols/stanols contribute to the maintenance of normal blood cholesterol levels 2".
The U.S. Food and Drug Administration (FDA) approved the following claim for phytosterols: "foods containing at least 0.4 grams per serving of plant sterols, eaten twice a day with meals for a daily total intake of at least 0.8 grams, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease".
- Competitive Advantages
- Water Dispersible Plant Sterols For Cholesterol Reduction
- New Palm Free Version
- Efficient Cholesterol Reduction
- High Phytosterols Concentration
- Readily Dispersible
- Fat Free Ingredient
Applications & Uses
- Markets
- Applications
- Food & Nutrition Applications
- Application
EU has approved the use of phytosterols in yellow fat spreads, milk type products, yogurt type products, soya drinks, rye bread, cheese type products and food supplements. FDA has authorized the use of phytosterols in conventional foods and nutraceuticals.
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- In Vivo Efficacy
LIPOPHYTOL®-P CHOLESTEROL REDUCTION
The effect of LIPOPHYTOL®-P (LP-P) on cholesterol reduction was studied in vivo using
knock out Apo E mice in a study conducted by Dr. Blanco at the Institut de Recerca de l'Hospital de la Santa Creu i San Pau" in Barcelona (Spain).
Three groups of mice were fed either i) a high fat diet (control), ii) a high fat diet with
LP-P or iii) a high fat diet with phytosterol esters.LIPOPHYTOLO-P SIGNIFICANTLY REDUCED THE CONCENTRATION OF VLDL+LDL CHOLESTEROL IN SERUM COMPARED TO THE CONTROL.
Results from this study showed that both LIPOPHYTOL®-P and phytosterol esters have significantly reduced the concentration of VLDL+LDL cholesterol in serum compared to the control.Concentration of VLDL +LDL cholesterol in serum expressed in mM.
LIPOPHYTOL®-P PROTECTIVE EFFECT AGAINST AORTIC LESIONS
The effect of LIPOPHYTOL®-P on aorta atherosclerotic lesions was examined on every
group of mice after 8 weeks of treatment. Heart and proximal aortas were removed and atherosclerotic lesions quantified.LIPOPHYTOL®-P RESULTED IN REDUCED DAMAGED AORTA, AN INDICATION OF ABILITY TO PROTECT ARTERIES.
Atherosclerosis damage test indicated that LIPOPHYTOL®-P was the most effective in
protecting the mice arteries from the harmful effects of the high fat diet.Atherosclerotic area measured in um2
