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Lipomize Liposomal Arbutin (B74)

Liposomal Arbutin (B74) contains liposomes made of phosphatidylcholine from sunflower lecithin and Arbutin. The liposomal delivery system drives the active ingredientmaking it reach deeper layers of the skin. Arbutin protects the skin from damages caused by free radicals. It is a skin whitening agent which eliminates the formation of melanin pigmentby inhibiting tyrosinase activity. Arbutin gives main properties: whitening effects, to treatsunburn marks and to regulate melanogenesis, anti-aging effectand UVB/UVC filter.

INCI Name: Arbutin, Citric Acid, Phosphatidylcholine, Tocopheryl Acetate, Xanthan Gum

Functions: Anti-Aging Agent, Protective Agent, UV Filter, Whitening Agent

Ingredient Origin: Natural Origin, Non-Animal Origin, Plant Origin, Vegetable Origin

Labeling Claims: Clean at Sephora, Natural, Naturally Derived, Ulta Beauty's Conscious Beauty

Benefit Claims: After-Sun Repair, Age & Dark Spot Reduction, Anti-Aging, Free Radical Scavenging, Improves Skin Permeability, Moisturizing, Repairing, Skin Protection, Skin Whitening, UV Protection

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Knowde Enhanced TDS

Identification & Functionality

Features & Benefits

Applications & Uses

Application Format
Skin Care Applications
Sun Care Applications
Product Formulation Incorporation

Incorporation : The liposomal active ingredients (AI) commercialized by Lipomize are liquid dispersions that can be mixed with the cream or gel matrix, in no more than a 5 or 10% respect to the final product. A higher percentage application could cause significant changes in the texture and/or viscosity of the matrix (noting that an important part of the liposomal dispersion given is water). Otherwise, a lower percentage application would naturally lead to a final product with a low concentration of AI transported in liposomes. Liposomes are entities relatively sensitive to temperature and oxidation, via direct sunlight and extended air exposure. Because of that, it is important to take into account the following comments:

  • It is preferred to incorporate the liposomal dispersion on the matrix in a last mixing stage at room temperature, prior to fractionating the product.
  • Keep the container with the liposomal dispersion open, as little time as possible.
  • Work away from direct sunlight. In general a liposomal active ingredient can perfectly coexist with a non-liposomal active ingredient within a cream or a gel. However, it is strongly recommended that during the elaboration of the final product, THESE ACTIVE INGREDIENTS (liposomal and non-liposomal) NOT BE MIXED BEFORE, but that they be incorporated sequentially into the matrix, homogenizing correctly between one aggregate and another. The following figure outlines the possible situations.

Properties

Physical Form
Odor
Characteristic
Appearance
Translucent to opaque viscous liquid
Chemical Composition
ValueUnitsTest Method / Conditions
Arbutin9.00 - 11.00%
Sunflower Phosphatidylcholine0.50 - 1.00%
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
Particle Size300 - 900nmDynamic Light Scattering
pH4.00 - 6.00Direct pHmeter
Microbiological Values
ValueUnitsTest Method / Conditions
EnterobactersAbsenceAOAC Performance Tested Nº 012001
Total Aerobicsmax. 1000CFU/mlAOAC Performance Tested Nº 010401
Yeasts and Molds Countmax. 1000CFU/mlAOAC Performance Tested Nº 092002

Regulatory & Compliance

Quality

All raw materials used comply with the laws and regulations quality requirements applicable. This product does not contain any physical, chemical or biological agent in such amounts that may pose a health risk to the final consumer.

Legal Note

LIPOMIZE SRL is not responsible for the improper use of this product. This includes, but is not limited to: use outside the expiration date, use in products for which it has not been recommended, use in quantity in which it has not been recommended.

Technical Details & Test Data

Process Information

Lipomize Liposomal Arbutin (B74) - Process Information


For simplicity, the CORRECT PROCESS shows the liposomal AI/non-liposomal AI sequence, but the reverse sequence can also be used. The importance lies in the correct and complete homogenization between the addition of the different AIs. Thermostability : Temperatures of up to 50°C for a short time do not affect the stability of the product.

Packaging & Availability

Packaging Information

Sanitized plastic container, sealed and opaque of 1L, 5L, 10L, 20L.

Storage & Handling

Shelf Life
18 Months
Storage & Shelf Life
  • Closed Packaging : Keep in a cool and dry place, away from direct sunlight.
  • Open Packaging : Suggested keep refrigerated below 25 °C. DO NOT FREEZE.
  • Shelf Life : 18 months after production in sealed original packaging. As it is a product with natural extracts of vegetable origin, it is possible to observe color differences between different batches. For the same reasons and with the passage of time, precipitates may appear in an amount not greater than 0.1% by weight, but in no case does it mean that the quality of the product has undergone alterations.