Enhanced TDS
Knowde-enriched technical product data sheet
Identification & Functionality
- Ingredient Name
- Pharma & Nutraceuticals Functions
- Ingredients
- Melatonin
- Product Families
- Product Characteristics
Appearance (upon reconstitution in deionized water) : Homogeneous, translucent dispersion.
Features & Benefits
- Benefit Claims (Health)
- Labeling Claims
- Why liposomal Melatonin?
Although melatonin is relatively soluble in aqueous solvents, the bioavailability of oral melatonin is relatively low. This is due to high first-pass clearance in the liver and low absorption in the gastrointestinal tract. Standard products feature melatonin in free form in which it is subject to these biological challenges. By encapsulating melatonin in liposomes and protecting it from premature degradation while enhancing its intestinal absorption, our product partially overcomes these issues, increasing the chance of it reaching the site of action.
- Melatonin health benefits
Sleep is crucial to a healthy life. Many different medications exist to treat sleep disorders, but these have serious side effects including dependency and cognitive impairment. Melatonin supplementation on the other hand is a safe and effective method to contribute to a faster sleep onset and normal sleep patterns. Melatonin is a naturally produced hormone that regulates the sleep-wake cycle. It is well tolerated and does not induce dependence. Furthermore, studies report that people using melatonin experience less severe jet lags, better self-recorded mood ratings and sleep parameters.
- Product Highlights
Highly effective
Our liposomal supplements are superior in terms of effectiveness due to our proprietary formulation process and liposomal technology.Science Based
Our scientists are world class experts in liposome technology and their clinical applications.Better efficacy
Non-toxic
Our liposomes are essentially non-toxic and biologically degradable.
Applications & Uses
- Applications
- Dosage Form
- Food & Nutrition Applications
Properties
- Appearance
- Light yellow to amber-colored cake (pieces or powder)
- Microbiological Values
- Specifications
- Note
Microbiological Condition : Incubated at 30°C for 48 hours.
| Value | Units | Test Method / Conditions | |
| Total Aerobic Colony Count | max. 2000 | cfu/g | - |
| Escherichia Coli | Absent | in 10 g | - |
| Enterobacteriaceae | Absent | in 10 g | - |
| Salmonella | Absent | in 25 g | - |
| Total Yeast and Mold Count | max. 100 | cfu/g | - |
| Value | Units | Test Method / Conditions | |
| pH (Reconstitution in Deionized Water) | 4.0 - 6.5 | - | pH meter |
| Melatonin | 16 -24 | mg/g | HPLC |
| Fat Free Lecithin | 127 - 265 | mg/g | HPLC |
| Tocopherol (and Derivatives) | min. 4.5 | mg/g | HPLC |
| Histidine | 6.2 - 9.3 | mg/g | NA |
| Trehalose (Cryoprotectant) | 194 - 291 | mg/g | NA |
| Inulin | 400 - 646 | mg/g | NA |
| Liposome Diameter (upon Reconstitution in Deionized Water) | 150 - 600 | nm | DLS |
| Polydispersity index (upon Reconstitution in Deionized Water) | max. 0.6 | - | DLS |
| Residual Water | max. 2 | % | Electrical conductivity |
| Residual Ethanol | max. 0.01 | % | GC |
Storage & Handling
- Shelf Life
- 2 years
- Instructions and Precautions
- This product is of hygroscopic nature. It should be stored in a tightly closed container in a dry and dark storage place at room temperature for 2 years.
- Avoid long exposure to air and opening in humid environments.
- Slight variations in color, taste and scent may occur among batches and are related to the source of CBD extract. These variations do not affect the product quality.