Knowde Enhanced TDS
Identification & Functionality
- Carrier
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
- Sustainability
Naturality according to ISO16128 99.5% natural origin content
Features & Benefits
- Benefit Claims
- Benefits
- Turning on the cellular alarm clock
- Mitochondrial power boost
- Anti-fatigue effect for active lifestyles
- Product Highlights
Science
- The skin can present a lower barrier function, water content and microcirculation in the early morning due to circadian rhythms. This explains why the skin looks dull and fatigued in the morning in comparison to the afternoon. Individuals that lead an active lifestyle want their skin to look its best around the clock. The protein JARID1a is a molecular switch that stimulates clock genes in the cell to activate important physiologic functions each day. It regulates mitochondrial activity, which is essential to generate the energy required for cellular processes. With aging, the circadian clock becomes dysregulated and mitochondria functionality is impaired.
- Dawnergy™ peptide increases JARID1a and clock genes levels in cultured cells and enhances early morning functions in skin models to levels typically found at noon. It can also provide an energizing effect on the mitochondrial activity of skin cells. As demonstrated in vivo, anti-fatigue effects could be observed with the ingredient, even after a night out, while a more radiant and smooth skin was measured.
Applications & Uses
- Markets
- Applications
- Skin Care Applications
- Use Level
- 1%
Properties
- Appearance
- Transparent solution containing 0.25% Nonapeptide-1.
- Soluble in
- Water
Regulatory & Compliance
- Certifications & Compliance