Juveleven™ peptide solution

Identification & Functionality

Carrier

Aqua,

Butylene Glycol,

Solvent-based

INCI Name

Acetyl Hexapeptide-51 Amide

Cosmetic Ingredients Functions

Protective Agent

Technologies

Cosmetic Ingredients

Product Families

Cosmetic Ingredients — Cosmetic Actives

Skin Actives

Features & Benefits

Benefit Claims

DNA Protection,

Improves Cell Longevity,

Promotes Youthful Skin,

Rejuvenating,

Repairing,

Rescue Of UV-Damaged Fibroblasts,

Stimulating,

Sun Protection

Labeling Claims

Clean at Sephora

Benefits

• Cell rejuvenation by over 10 years
• Key element in preserving the vital code
• Decreases DNA damage in vivo

Product Highlights

Science

• The maintenance of DNA integrity is essential for the proper functioning and survival of organisms. DNA strands suffer from the constant challenge of endogenous and exogenous genotoxic agents as well as replication errors. UV-induced lesions may result in the formation of cyclobutane pyrimidine dimers (CPDs), a well-known form of pyrimidine dimers. Such damage can distort the structure of the DNA, altering its transcription and replication. Checkpoint pathways monitor DNA structure and control cellcycle arrest allowing for repair and continue progression if everything is correct, before a mistake can be propagated to daughter cells.
• FOXO3a acts as a master regulator that determines cell fate once damage is detected. Depending on the severity of the damage, this key transcription factor forces a state of quiescence in cells signaling for repair of errors or apoptosis. The active form of FOXO3a increases the level of well known antioxidants, induces the expression of genes involved in DNA-damage repair and triggers cell death when necessary. juveleven™ peptide imitates the activity of FOXO3a, increasing the expression of several genes involved in DNA repair pathways. It also provides protection to cells and rejuvenates fibroblasts, retarding their senescence.

Applications & Uses

Markets

Personal Care

Applications

Personal Care — Beauty & Care

Skin Care,

Sun Care

Application Format

Leave On

Sun Care Applications

After Sun Products

Use Level

2%

Applications

Juveleven™ peptide can be incorporated into daily skin care formulations to protect the skin from DNA-damaging elements and enhance cellular longevity and vitality, contributing to younger looking skin.

Properties

Physical Form

Liquid,

Solution

Appearance

Transparent solution containing 0.05% Acetyl Hexapeptide-51 Amide.

Soluble in

Water