Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Attributes
- Frees skin, scalp and hair from the effects of the exposome.
- Rich in Azukides™ natural peptides.
- All-in-one skin, scalp and hair care solution.
Cosmetic active ingredient obtained through biotechnology from organic azuki beans, rich in Azukides™ natural peptides. It can protect the skin, scalp and hair against exposome-induced stressors and empower users to explore and enjoy the great outdoors.
Applications & Uses
- Markets
- Hair Care Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 1 - 2%
Properties
- Appearance
- Light yellow to light orange transparent solution
- Soluble in
- Water
- Composition
| Value | Units | Test Method / Conditions | |
| Phaseolus Angularis Seed Extract | 0.2 | % | — |
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Technical Details
The exposome is the totality of exposures to which an individual is subjected throughout their life. The most important external exposome factors that can potentiate the aging appearance include pollution, sun radiation, pollen, greenhouse gasses and global warming. As concerns for climate change grow, so do concerns for the damage that these factors can cause to the skin and hair, including protein carbonylation, lipid peroxidation and DNA damage, which can negatively impact the skin and hair condition.
Xpozuki™ biotech ingredient showed in vitro to min- imize the exposomeinduced stress on skin cells and hair follicles, while supporting keratinocyte proliferation for an improved barrier protection. Ex vivo, it showed to protect multiethnic hair from the exposome with additional benefits related to dye and heat-induced damage. In vivo on multiethnic volunteers, it improved barrier function, skin tone and redness, and texture homogeneity. On hair, it protected against split ends, frizz, and fiber alignment.
- In Vitro and Ex Vitro Efficacy
- Minimized exposome stress-induced protein carbonylation on hair follicles.
- Multiethnic hair protection from exposome- induced protein carbonylation.
- Maintaining a healthy hair structure despite stress caused by heat and hair dyes.
- Preventing hair lipid peroxidation caused by solar radiation
- Exposome protection against oxidation.
- 100% protection against 8-oxo-7,8-dihydro-2’- deoxyguanosine.
- 59% protection against 8-hydroxyguanosine.
- Facilitates 27.6% increase in keratinocyte proliferation.
- Increased skin cell viability under exposome conditions.
- In Vivo Efficacy
Skin Care
62 multiethnic female volunteers applied a cream with 2% Xpozuki™ biotech ingredient or a placebo cream on the face, twice a day for 28 days.
More protected skin barrier and improved skin appearance
- Barrier function protection
- Improved skin tone homogeneity and skin brightness
- Minimized skin redness
- Improved surface texture irregularities
Hair Care
62 multiethnic female volunteers applied a hair leave on spray serum with 2% Xpozuki™ biotech ingredient or a placebo spray serum on the hair, once a day for 14 days.
Improved multiethnic hair vitality
- Less split ends
- Improved hair fiber alignment
- Frizz reduction
- Reduced hair volume while improving curl definition