Knowde Enhanced TDS
Identification & Functionality
- Carrier
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 91722-21-3
- EC No.
- 294-422-4
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Highlights
Science
Among the many beauty buzzwords, retinoids are some of the most used and studied ingredients that show promise in minimizing skin aging and improving the skin tone. They are mainly known to enhance skin regeneration, to improve the extracellular matrix (ECM), and to activate the skin’s antioxidant response, altogether providing a complete skin rejuvenating effect. Nevertheless, the topical application of retinoids is also associated with undesired effects related to skin inflammation, which causes many consumers to avoid their use and opt for gentler alternatives, such as bakuchiol.
Stevisse™ advanced botanical ingredient showed to induce the expression of genes related to the pathway of retinoids, in vitro. As a result, the ingredient helped to promote similar activities to retinoic acid, such as skin regeneration, enhancement of ECM proteins, and the boost of cellular resistance to oxidative stress, all of this while minimizing the skin inflammation associated with retinoids, similarly to bakuchiol. In vivo, the ingredient helped minimize the appearance of wrinkles, it homogenized the skin tone and reduced the number of dark spots.
- Product Benefits
- The eco-friendly Phenobio™ subcritical water technology was applied to locally-sourced organic stevia to obtain an extract rich in polyphenols
- Organic certified starting raw material
- Gentler and natural alternative to retinoids
- Visibly fades wrinkles and evens skin tone
- Fully sustainable and traceable, powered by blockchain technology
Applications & Uses
- Markets
- Applications
- Skin Care Applications
- Use Level
- 2%
Properties
- Physical Form
- Appearance
- Clear liquid
- Soluble in
- Water
- Typical Properties
- Specifications
| Value | Units | Test Method / Conditions | |
| Natural Origin | 100 | % | ISO 16128 |
| Value | Units | Test Method / Conditions | |
| Stevia Rebaudiana Leaf | 4 | % | — |
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- In Vitro Efficacy
Retinoid-Like Mechanism
- Helping to boost the bioavailability of retinol and reduce its use in formulations
- Gentler alternative to retinoids, similarly to bakuchiol
- In vitro induction of genes related to the retinoid pathway
- In Vivo Efficacy
Bringing Out The Skin’s Natural Beauty: 21 women applied a cream with 2% Stevisse™ advanced botanical ingredient on half of their face and a placebo cream on the other half, twice a day. After 28 days of treatment, wrinkle area and length, skin tone homogeneity and dark spots were evaluated.
Minimized appearance of wrinkles: Photographs were analyzed for the measurement of the area and length of wrinkles.
After 28 days: Naturally-diminished wrinkles: Decrease of up to 87.3% and 85.3% in wrinkle area and length, respectively.
Skin tone evening effect: Facial skin color distribution and the amount of pigmented spots were evaluated by a specific software for image analysis of the skin characteristics.
After 28 days: More uniform skin tone with a reduced appearance of dark spots