Knowde Enhanced TDS
Identification & Functionality
- Active Component
- Ingredient Name
- Ingredient Origin
- Pharma & Nutraceuticals Functions
- Ingredients
- Salmon Cartilage Extract
- Product Families
Features & Benefits
- Benefit Claims (Health)
- Labeling Claims
- Product Highlights
- Features proteoglycans, a key component of connective tissues such as cartilage, bones, and skin, which have been extensively researched in joint, skin, and immune system health.
- Unique extraction technologies have made naturally-sourced proteoglycan effective at low dosage.
- Functions
- Joint
- Beauty support
- Skin support
- Clinically Researched Benefits
- Supporting joint comfort, mobility, and range of motion
- Improvements in cartilage quality and composition
- Helps improve skin conditions associated with aging and moisturization
- Supports anti-inflammatory effects in the intestines that alter intestinal microbiota
- Numerous safety studies with no adverse effects
Applications & Uses
- Markets
- Food & Nutrition Applications
Regulatory & Compliance
Technical Details & Test Data
- Mechanism of Action
- There are several hypotheses regarding how sPG works.
- Skin: sPG induces the production of collagen and hyaluronan and enhances the proliferation of keratinocytes (skin cells).
- Joints: sPG spurs the production of chondrocytes (cartilage cells) by helping them proliferate and differentiate.
- Skin and joints: sPG also stimulates immunity in the gut and lymphatic system, which helps maintain a balance of excitatory and inhibitory cytokines.
Safety & Health
- Safety
In Japan, salmon cartilage is consumed as a traditional tonic for joint health and general health. Numerous animal studies on purified proteoglycan, including a 90-day repeated dose toxicity study in rats, have shown no adverse effects and found it is safe for human consumption.