Knowde Enhanced TDS
Identification & Functionality
- Ingredient Name
- Pharma & Nutraceuticals Functions
- CAS No.
- 625-08-1
- Ingredients
- 3-Hydroxyisovaleric Acid
- EC No.
- 626-699-8
Features & Benefits
- Food Ingredients Features
- What is BetaTOR
- Having proper nutrition, training, and supplementation is key when optimizing your training results. With strong research and proven results, the choice is clear. BetaTOR can help you maximize your training results.
- BetaTOR is the pure, free acid form of HMB (beta-hydroxy-beta-methylbutyrate). BetaTOR is naturally produced in our bodies during the metabolism of the essential amino acid leucine, which is naturally found in foods such as beef, fish, soybeans, and alfalfa.
- Scientists have studied and shown the positive effects of CaHMB on increasing strength, lean mass, and decreasing muscle damage and improving recovery after rigorous exercise for decades. This easily deliverable form of HMB has been the mainstay of HMB used in supplements. New developments in manufacturing allowed the scientists to theorize that HMB as BetaTOR could be a very effective method of delivery for HMB.
- In 2009, scientists started studying the kinetics of this delivery form, and in 2011 published their results showing faster absorption, increased blood levels of HMB, and increased clearance to tissues. This revolutionary study on the new delivery form of HMB has now resulted in several clinical studies showing safety and efficacy. The results from using BetaTOR attest to what the scientists thought, this new delivery form is superior to the CaHMB form.
- Benefits of BetaTOR Sports Supplements
Clinical research has shown that supplementing with BetaTOR during an intense training cycle can improve strength, power, body composition, aerobic performance, and recovery.
Research has shown that supplementing with BetaTOR can help you maximize your strength gains from intense training.
In a study conducted by Wilson et al. (2014), highly trained men underwent an intense 12-week workout program, which included an overreaching phase in weeks 9 and 10. Over the study, BetaTOR-supplemented participants increased their total strength as measured by the sum of their 1-RM (repetition maximum) in bench press, squat, and deadlift by 77.1 kg (170 lbs.) while the placebo-supplemented participants gained only 25.3 kg (56 lbs.). This was an increase in strength gained of over 200% with BetaTOR.
Supplementing with BetaTOR during an intense training program has been proven to blunt muscle damage and aid in muscle recovery
Beginning an exercise program, or taking your exercise program to the next level induces stress and causes muscle damage. BetaTOR has been proven to blunt muscle damage to help recovery when beginning your training. The study by Wilson et al. (2013) showed that BetaTOR reduced the increase in serum creatine kinase (CK) in highly-trained participants performing a rigorous training program. Serum CK rose 329% in the placebo-supplemented participants 48 hours after initiating training while the increase in BetaTOR-supplemented participants was only 104% indicating much less muscle damage with BetaTOR. During weeks 9 and 10 of the training, an overreaching phase was implemented and the training frequency and intensity was again increased. BetaTOR again blunted the rise in serum CK and muscle damage seen with this change in intensity of training (Wilson et al., 2014). BetaTOR protects your muscle during intense training and helps you recover faster.
The study also measured Perceived Recovery Status (PRS). In this subjective measure, participants are asked to rate their recovery and readiness to train again on a scale of 1 to 10. Consistent with the objective measure of serum CK, PRS scores showed that BetaTOR-supplemented participants were significantly more ready to train in the next session than the placebo-supplemented participants. BetaTOR helps your muscles recover faster, so you can train harder in your next session.
Improve your peak muscle power performance with BetaTOR
BetaTOR increases Wingate Peak Power by 54%
The development of muscle power is important in virtually every sport. In the 12-week study by Wilson et al. (2014), power was measured using a modified Wingate peak power cycling test as well as through the vertical jump test. Over the 12-week study, BetaTOR supplementation resulted in an 18% increase in Wingate power compared with only a 12% increase in placebo-supplemented participants. BetaTOR resulted in a 54% increase in Wingate power over training alone.BetaTOR increases Vertical Jump Power by 58%
Vertical Jump power is another measure of the explosive power of muscle contraction. Similar to the Wingate peak power test, BetaTOR supplementation also increased Vertical Jump power by 19% while placebo-supplemented participants only saw a 12% increase resulting in a 58% increase in Vertical Jump power with BetaTOR over training alone.
Improve aerobic performance from high-intensity training with BetaTOR.
A recent study conducted by Robinson et al. (2014) examined the effects of BetaTOR in men and women undergoing a high-intensity interval training (HIIT) program on indicators of aerobic performance. Over the 4-week study participants taking BetaTOR had increased oxygen uptake (VO2peak) and increased ventilatory threshold when compared with placebo-supplemented participants. The authors concluded that HIIT combined with BetaTOR supplementation resulted in greater benefits in improving indicators of aerobic metabolism than HIIT alone.
Incorporating BetaTOR into an intense training cycle has shown to help improve body composition by building muscle and losing body fat.
Supplementing with BetaTOR has shown to improve body composition by increasing both lean muscle mass gain and body fat loss.
Body composition in strength-training men was measured using dual x-ray absorptiometry (DXA, the gold standard) over a 12-week study (Wilson et al., 2014). BetaTOR-supplemented participants gained 7.4 kg (over 16.3 lbs.) of lean body mass compared with placebo-supplemented participants who gained 2.1 kg (4.6 lbs.), a 250% increase in lean muscle mass gain. Not only did the participants build more lean muscle mass, they lost more fat mass. BetaTOR supplementation resulted in a 5.4 kg (11.9 lbs.) fat mass loss while placebo-supplemented participants lost only 1.7 kg (3.7 lbs.) of fat mass, a 210% increase in fat loss.
Studies have shown that BetaTOR also boosts muscle thickness.
Muscle thickness is another measure of muscle hypertrophy. Quadriceps thickness was measured by ultrasonography, and BetaTOR-supplemented participants had a 14.3% increase in quadriceps thickness compared with placebo-supplemented participants who only had a 4.8% increase in thickness. BetaTOR supplementation resulted in a 200% increase in muscle thickness compared with placebo supplementation over the 12-week study
- Maximize Your Results
Training is a potent anabolic stimulus, which ultimately dictates muscle hypertrophy and strength gains achieved. However, your training is limited by your ability to recover. BetaTOR is a supplement that helps shifts the balance of protein synthesis and protein degradation in your favor and allows you to recover faster so you can maximize your training volume and frequency, thus maximizing your gains .As we adapt to the training stimulus, the program needs to be cycled or periodized to get the greatest stimulus. This can be accomplished with linear or non-linear periodization. The figure below shows how non-linear periodization provides the greatest stimulus and gains in muscle hypertrophy and strength. But if recovery time is limited, this intense training can lead to overtraining. This is where BetaTOR can play an important role and minimize your recovery time to maximize your gains.
Applications & Uses
- Markets
- Applications
- Food & Nutrition Applications
- How BetaTOR Works
When optimizing your training performance, the rate of muscle protein turnover plays a key role in your results. When protein synthesis is equal to your protein breakdown, there is no net gain in muscle protein.
BetaTOR aids in increasing muscle protein by two mechanisms. BetaTOR decreases muscle protein breakdown through the ubiquitin-proteasome proteolytic pathway. BetaTOR also increases muscle protein synthesis through the mTOR pathway.
Decrease Muscle Protein Breakdown
BetaTOR decreases muscle protein breakdown at a molecular level caused from intense training.
Rigorous exercise has been shown to increase muscle protein breakdown through the ubiquitin-proteasome proteolytic pathway. BetaTOR decreases the key regulative components and activity of the ubiquitin-proteasome proteolytic pathway, which results in less muscle protein loss. In a recent clinical study, BetaTOR decreased protein breakdown in muscle by 57% (Wilkinson et al., 2013). While the exact mechanism of the effect on the ubiquitin pathway is not currently known, studies in both animal models and humans have shown the same effect, reduced protein breakdown, which helps maintain more muscle mass.Enhance Muscle Protein Synthesis
BetaTOR stimulates muscle protein synthesis through multiple mechanisms, including the mTOR pathway, which stimulates initiation of protein synthesis.While the initiation of myofibrillar protein synthesis is influenced by a number of factors, mTOR is a key regulatory factor that results in a direct increase in myofibrillar protein synthesis. Myofibrillar proteins are the proteins in muscle that cause muscles to contract and are responsible for the strength of the muscle contraction. BetaTOR has been shown to increase the phosphorylation of mTOR, thus activating the mTOR signaling pathway in muscle. The mTOR then stimulates, or up-regulates, the initiation of protein synthesis in the muscle. Studies have shown that supplementing with BetaTOR increases protein synthesis up to 70% (Wilkinson et al., 2013), and results in a 12-week study show increases in lean mass of 250% greater than placebo and weight training alone (Wilson et al., 2014).
As a result of these mechanisms, BetaTOR increases muscle protein in your body to help aid strength, power, improve body composition, aerobic performance, and reduce recovery time. Learn more in depth about the benefits
Safety & Health
- BetaTOR Safety
As an athlete you want to optimize your training results the best way you can without having negative or detrimental effects to your health. Clinical studies conducted with BetaTOR have shown no untoward effects of the supplementation on blood chemistries or hematologies. In addition, an extensive toxicity study using dosages more than 10-fold the recommended dosage in humans showed no significant clinical findings, which would indicate no harmful effects of BetaTOR supplementation. BetaTOR provides a pure source of HMB, and decades of safety studies have been published and attest to the safety of HMB as CaHMB. With CaHMB, no untoward clinical effects have been observed, and in fact, only health positive effects have been reported with supplementation.
Packaging & Availability
- Where to Find BetaTOR
Sports Nutrition Supplement containing the clinically proven muscle-building ingredient BetaTORBetaTOR is sold Worldwide at a variety of locations. To find out where you can purchase BetaTOR products