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Neocel® Microcrystalline cellulose colloidal grades are water-dispersible, water-insoluble hydrocolloid products. It is used widely in pharmaceutical and food industries.Neocel is co-processed microcrystalline cellulose and specific grades of carboxymethylcellulose sodium (NaCMC). Microcrystalline cellulose is prepared by partial depolymerization of high purity alpha cellulose by mineral acids. The crystalline portions of the fiber, after being subjected to wet mechanical processes, are co-processed with NaCMC to form colloidal microcrystalline cellulose. NaCMC serves as a protective colloid and aids in the dispersion of the product.

Chemical Name: Cellulose, Microcrystalline

CAS Number: 9004-34-6

Functions: Emulsifier, Stabilizer, Suspending Agent, Thickener, Viscosity Modifier

Dosage Form: Creams, Spray, Suspension, Syrups

Synonyms: Crystalline cellulose, Micro Fibril Cellulose, Pyrocellulose

    Knowde Enhanced TDS

    Identification & Functionality

    Chemical Family
    CAS No.
    9004-34-6
    EC No.
    232-674-9

    Features & Benefits

    Benefits
    • Unique suspension, thickening and emulsifying mechanism
    • High compatibility with other ingredients
    • Dispersible in cold water
    • Thermal stable
    • Applicable in wide range of pH value
    • Excellent texture modifier

    Applications & Uses

    Application

    IN DRUG
    Neocel® functions as a suspending agent/thickener and emulsion stabilizer, primary used in syrups, suspensions such as antacid preparations, emulsions, nasal sprays and creams.

    IN FOOD
    Neocel® finds wide applications in food such as dairy product, beverage, bakery product, sauce, dressing and processed meat.

    Instructions for Use

    Neocel® should be fully dispersed in the solution to develop its functional properties, here are tips for Neocel dispersion.

    1. Adequate shear force must be applied to disperse Neocel. High-speed mixer and homogenizer are highly recommended.
    2. The preferred order of addition is to add Neocel to water before other ingredients.
    3. Use soft water rather than hard water since electrolytes can inhibit the dispersity of Neocel.
    4. If the pH of product is below 3.5, a protective gum (e.g. xanthan gum) is suggested to be added before Neocel to prevent flocculation.
       

    Technical Details & Test Data

    Mechanism of Stabilization

    Neocel® forms a three-dimensional structure after properly dispersion. The MCC particles are spread and create a network that stabilizes the system.

    NEOCEL® - Mechanism of Stabilization