company tower banner
Nicobrand Company Logo

Nicobrand Nicotine Polacrilex

Nicobrand Nicotine Polacrilex is an ion-exchange resin complex containing nicotine USP/EP. Nicotine Polacrilex or Nicotine Resinate as it is known in Europe is specifically formulated to allow the controlled release of nicotine into the body.

Chemical Name: Nicotine Polacrilex

Certifications & Compliance: European Pharmacopeia (Ph. Eur.), United States Pharmacopeia (USP), cGMP

Technical Data Sheet
  • TypeDocument Name
View All Documents

Knowde Enhanced TDS

Identification & Functionality

Chemical Name
CAS No.
96055-45-7
EC No.
619-191-2
Identification
  1. Glycerol color test must be positive.
  2. Infrared spectrum of released Nicotine must be comparable to the reference spectrum produced by a similar preparation of nicotine extracted from Nicotine Bitratrate Dihydrate USP Reference standard
  3. Infrared spectrum of polymer resin must be comparable to a reference spectrum of Polacrilex Resin RS
  4. Complies with nicotine release test
  5. The retention time of the major peak of the Sample Solution corresponds to that of the Standard Solution, obtained in the test for Nicotine Content/Chromatographic Purity

Applications & Uses

Properties

Physical Form
Appearance
White or slightly yellowish fine powder, free from contamination
Typical Properties
ValueUnitsTest Method / Conditions
Water Contentmax. 5.0%-
Nicotine Release (Nicotine Released in 10 Minutes)min. 70.0%-
Nicotine Content17.10 - 20.70%-
Nicotine Content (Of Label Claim on Anhydrous Basis)95.0 - 115.0%-
Glycerol Content10.0 ± 1.0%-
Loss on Dryingmax. 7.0%-

Regulatory & Compliance

Technical Details & Test Data

Chromatographic Purity (HPLC)
Nicotine N'-oxide: ≤ 0.3%
Cotinine: ≤ 0.3%
Nornicotine: ≤ 0.3%
Anatabine: ≤ 0.3%
Myosmine: ≤ 0.3%
Anabasine: ≤ 0.3%
ß-Nicotyrine: ≤ 0.3%
Any other impurity: ≤ 0.10%
Sum of all impurities: ≤ 0.8%

Packaging & Availability

Packaging
Product Batch Quantities Pack Size
Nicotine Polacrilex 18% Up to 139kg 1kg and 25kg