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PolyKoVidone® XL

1 of 4 products in this brand
NKY Pharma PolyKoVidone XL are an essential ingredient to formulating highly effective pharmaceutical products. The polymers are produced in a state of the art manufacturing facility operating under full cGMP compliance. In addition, all physical handling and packaging of powders is conducted in class-D clean rooms with specific attention placed on reducing the risk of any potential particulate/foreign matter contamination. PolyKoVidone® possesses dual binding and disintegration properties while enhancing active solubilization. The product is used in the Pharma applications.

Chemical Name: Polyvinyl Pyrrolidone Copolymer

CAS Number: 9003-39-8

Functions: Complexing Agent, Disintegrant, Solubilizer, Stabilizer, Suspending Agent

Dosage Form: Capsules, Dispersions, Granules, Suspension, Tablets

Certifications & Compliance: British Pharmacopeia (BP), European Pharmacopeia (Ph. Eur.), Indian Pharmacopeia, Japan Pharmacopeia (JP), Korean Pharmacopeia, United States Pharmacopeia (USP), cGMP

Synonyms: 1-Vinyl-2-pyrrolidinone polymer, 1-Vinyl-2-pyrrolidone homopolymer, 1-Vinyl-2-pyrrolidone polymer, 1-Vinylpyrrolidin-2-one homopolymer, n-Octyl mercaptan-N-vinylpyrrolidone copolymer, N-Vinyl-2-pyrolidone homopolymer, N-Vinyl-2-pyrrolidinone homopolymer, N-Vinyl-2-pyrrolidone homopolymer, N-Vinyl-2-pyrrolidone polymer, N-Vinylbutyrolactam polymer, N-Vinylpyrrolidinone homopolymer, N-Vinylpyrrolidinone polymer, N-Vinylpyrrolidone homopolymer, N-Vinylpyrrolidone polymer, Poly(1-vinyl-2-pyrrolidinone), Poly(1-vinyl-2-pyrrolidone), Poly(1-vinylpyrrolidinone), Poly(N-vinyl-2-pyrrolidinone), Poly(N-vinyl-2-pyrrolidone), Poly(N-vinyl-γ-butyrolactam), Poly(N-vinylbutyrolactam), Poly(N-vinylpyrrolidinone), Poly(N-vinylpyrrolidone), Poly(vinylpyrrolidinone), Poly(vinylpyrrolidone), Polyvinyl polypyrrolidone, Polyvinylpyrrolidone, Povidone, Vinylpyrrolidinone polymer, Vinylpyrrolidone homopolymer, Vinylpyrrolidone polymer

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    Knowde Enhanced TDS

    Identification & Functionality

    Chemical Name

    Polyvinyl Pyrrolidone Copolymer

    Pharma & Nutraceuticals Functions

    Complexing Agent,

    Disintegrant,

    Solubilizer,

    Stabilizer,

    Suspending Agent

    CAS No.
    9003-39-8
    EC No.
    618-363-4
    Technologies

    Pharmaceuticals & Nutraceuticals

    Product Families

    Pharmaceuticals & Nutraceuticals — Excipients

    Binders & Disintegrants,

    Emulsifiers & Stabilizers,

    Formulation & Processing Aids,

    Solvents & Solubilizers

    Features & Benefits

    Product Highlights
    • Hygroscopic.
    • Insoluble in water, acid, alkaline and all other common solvents.
    • Swells rapidly in water without gel formation.
    • Improves flowability and plasticity.
    • Strong particle compressibility.
    • Non-ionic; Chemically inert; Low Peroxide content.

    Applications & Uses

    Markets

    Healthcare & Pharma

    Applications

    Healthcare & Pharma — Drug Delivery & Care Solutions

    Oral,

    Transdermal

    Dosage Form

    Capsules,

    Dispersions,

    Granules,

    Suspension,

    Tablets

    Manufacturing Technology

    Direct Compression,

    Dry Granulation,

    Wet Granulation

    Recommended Uses and Known Applications
    • Super disintegrant; due to its excellent swelling characteristics in water, PolyKoVidone® can be used as water insoluble disintegrant for wet and dry granulation processes. The material can be added either before or after granulation in direct compression tableting processes. It exhibits high capillary activity and pronounced hydration capacity, without the formation of gel.
    • Solubility enhancer; PolyKovidone® increasing the solubility of poorly soluble drugs via co-evaporation processes.
    • Suspension stabilizer; PolyKoVidone® increasing the viscosity and improves the dispersion properties to reduce the sedimentation rate of drugs, meanwhile increasing the re-dispersibility of said sediment. Suitable for liquid and instant oral preparations.
    • Complexing agent of drug ingredients; PolyKoVidone® stabilizes active ingredients in pharmaceutical products, improving drug solubility and bioavailability.

    Properties

    Physical Form

    Powder,

    Solid

    Regulatory & Compliance

    Certifications & Compliance

    British Pharmacopeia (BP),

    European Pharmacopeia (Ph. Eur.),

    Indian Pharmacopeia,

    Japan Pharmacopeia (JP),

    Korean Pharmacopeia,

    United States Pharmacopeia (USP),

    cGMP

    Grade

    Pharma Grade