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Verbasnol™ is an advanced age-defying botanical derived from Rehmannia glutinosa that helps boost the skin’s natural ability to fight free radical damage and nourish the skin with antioxidants for a radiant glow. It's validated by HPLC as a true verbascoside [a caffeoyl phenylethanoid glycoside (C29H36O16)].

Ingredient Name: Rehmannia Glutinosa

Active Component: Verbascoside

Functions: Dietary Supplement

    Knowde Enhanced TDS

    Identification & Functionality

    Active Component
    Ingredient Name
    Pharma & Nutraceuticals Functions

    Features & Benefits

    Key Benefits

    Reduces Acne

    Reduces Inflammation

    Reduces Yeast Growth

    Beneficial Nutrients

    Antioxidants

    Fights Environmental Factors

    The Science Behind Verbasnol™

    A verbascoside is characterized as an effect scavenger of biologically active free radicals and an inhibitor of lipid peroxidation. Fewer free radicals invading the skin layers mean healthier, smooth, and lustrous skin.

    In research studies, verbascoside has shown to be effective for:

    • Anti-Acne*
    • Anti-Aging*
    • Anti-Erythema*
    • Anti-Inflammatory*
    • Anti-Malassezia*
    • Anti-Oxidant*
    • Collagenase Inhibitor*
    • Sebum Regulating*
    • Tyrosinase Inhibitor*

    In a study on human fibroblast cells (the cells that comprise your top layer of skin), verbascoside “possessed significant photoprotective activities, reducing MMP and IL-6 levels while improving type-I procollagen synthesis”.

    Applications & Uses

    Applications
    • Emulsions
    • Serums
    • Creams
    • Capsules
    • Gels
    How Verbascoside Works

    Propionibacterium acnes (P. acnes) is associated with acne lesions and leads to cutaneous inflammation. Verbascoside has anti-acne activity by inhibiting P. acnes growth. Verbascoside has shown to decrease the pro-inflammatory chemokine IL-8 expression to exert anti-inflammatory activity on skin cells.

    Furthermore, verbascoside may inhibit Malassezia furfur (a lipophilic yeast) growth that is implicated in numerous skin irritations, including pityriasis versicolor, seborrheic and atopic dermatitis, dandruff and folliculitis.

    Verbascoside exerts a remarkable antioxidative property by scavenging the free-radical species that are implicated in oxidative stress in human skin aging. Furthermore, the glycoside also inhibits the production of tyrosinase that catalyzes the production of melanin to darken the skin. It's also noteworthy to mention that verbascoside may inhibit the 5α-reductase activity of skin sebum production to control androgen homeostasis in human skin.